Zebrafish Models for Dyskeratosis Congenita Reveal Critical Roles of p53 Activation Contributing to Hematopoietic Defects through RNA Processing

TCAB1: Driving telomerase to Cajal bodies

(2011) Andrew S. Venteicher et al.   CELL CYCLE

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

(2011) F. Zhong et al.   GENES & DEVELOPMENT

Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations

(2011) Tom J. Vulliamy et al.   PLoS One

Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects

(2010) Nadia Danilova et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mutations in C16orf57 and normal-length telomeres unify a subset of patients with dyskeratosis congenita, poikiloderma with neutropenia and Rothmund–Thomson syndrome

(2010) Amanda J. Walne et al.   HUMAN MOLECULAR GENETICS

Telomere Length and Risk of Incident Cancer and Cancer Mortality

(2010) Peter Willeit et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing

(2010) Faizan Alawi et al.   MOLECULAR CARCINOGENESIS

Box H/ACA Small Ribonucleoproteins

(2010) Tamás Kiss et al.   MOLECULAR CELL

Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation

(2009) Klelia D. Salpea et al.   ATHEROSCLEROSIS

Dyskeratosis congenita, stem cells and telomeres

(2009) Michael Kirwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cancer in dyskeratosis congenita

(2009) B. P. Alter et al.   BLOOD

Dyskerin Ablation in Mouse Liver Inhibits rRNA Processing and Cell Division

(2009) J. Ge et al.   MOLECULAR AND CELLULAR BIOLOGY

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

(2008) Sharon A. Savage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family

(2008) N. Danilova et al.   BLOOD

A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis

(2008) Shintaro Imamura et al.   PLoS One

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers

(2008) Shuji Kishi et al.   PLoS Genetics