Shiga Toxin Binding to Glycolipids and Glycans

Shiga toxin (Stx)1B and Stx2B induce von Willebrand factor secretion from human umbilical vein endothelial cells through different signaling pathways

(2011) F. Liu et al.   BLOOD

Globotriaosylceramide (Gb3) content in HeLa cells is correlated to Shiga toxin-induced cytotoxicity and Gb3 synthase expression

(2011) In-Sun Shin et al.   BMB Reports

Shiga Toxin Subtypes Display Dramatic Differences in Potency

(2011) Cynthia A. Fuller et al.   INFECTION AND IMMUNITY

Cholesterol modulates glycolipid conformation and receptor activity

(2011) Daniel Lingwood et al.   Nature Chemical Biology

Different Classes of Antibiotics Differentially Influence Shiga Toxin Production

(2010) C. M. McGannon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification and Characterization of the Carbohydrate Ligands Recognized by Pertussis Toxin via a Glycan Microarray and Surface Plasmon Resonance

(2010) Scott H. Millen et al.   BIOCHEMISTRY

Comparison of Binding Platforms Yields Insights into Receptor Binding Differences between Shiga Toxins 1 and 2

(2010) Michael J. Flagler et al.   BIOCHEMISTRY

Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

(2010) J. Huang et al.   BLOOD

Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide

(2010) S. D. Zumbrun et al.   INFECTION AND IMMUNITY

A Major Fraction of Glycosphingolipids in Model and Cellular Cholesterol-containing Membranes Is Undetectable by Their Binding Proteins

(2010) Radhia Mahfoud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Cholesterol Constrains Glycolipid Conformation for Optimal Recognition of Alzheimer's β Amyloid Peptide (Aβ1-40)

(2010) Nouara Yahi et al.   PLoS One

Molecular Basis of Differential B-Pentamer Stability of Shiga Toxins 1 and 2

(2010) Deborah G. Conrady et al.   PLoS One

Factors Affecting Protein-Glycan Specificity: Effect of Spacers and Incubation Time

(2009) Daniel M. Lewallen et al.   CHEMBIOCHEM

Hemolytic uremic syndrome: pathogenesis and update of interventions

(2009) Marina S Palermo et al.   Expert Review of Anti-Infective Therapy

Globotriaosyl ceramide receptor function - Where membrane structure and pathology intersect

(2009) C.A. Lingwood et al.   FEBS LETTERS

Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays

(2009) Simon Rinaldi et al.   GLYCOBIOLOGY

Comparison of the results obtained by ELISA and surface plasmon resonance for the determination of antibody affinity

(2009) Laurence Heinrich et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Treatment options for HUS secondary to Escherichia coli O157:H7

(2009) Martin Bitzan   KIDNEY INTERNATIONAL

Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology

(2009) Fahima Khan et al.   KIDNEY INTERNATIONAL

Differentiation between Structurally Homologous Shiga 1 and Shiga 2 Toxins by Using Synthetic Glycoconjugates

(2008) Ramesh R. Kale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS)

(2008) Johanna Scheiring et al.   PEDIATRIC NEPHROLOGY

Chronic Kidney Disease in Children

(2008) Dilys A. Whyte et al.   PEDIATRICS IN REVIEW

The molecular face of lipid rafts in model membranes

(2008) H. J. Risselada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA