Article
Surgery
Yuanjing Chen, Yimeng Chai, Bo Yin, Xinyu Zhang, Xuefeng Han, Lei Cai, Ningbei Yin, Facheng Li
Summary: The study showed that washing lipoaspirate can improve fat graft survival, promote adipogenesis and angiogenesis, possibly by relieving inflammation, reducing oxidative stress injury and inhibiting apoptosis.
AESTHETIC PLASTIC SURGERY
(2022)
Article
Biochemistry & Molecular Biology
Xiangdong Zhang, Xiaoxuan Jin, Yibao Li, Mimi Xu, Yao Yao, Kaiyang Liu, Chijuan Ma, Yuchen Zhang, Jiangjiang Ru, Yunfan He, Jianhua Gao
Summary: This study aims to clarify the process of extracellular matrix (ECM) remodeling and its relationship with adipocyte survival and adipogenesis after fat grafting. The results demonstrate the various preservation modes of fat grafts after transplantation and underscore the importance of macrophage-mediated ECM remodeling in graft preservation.
Article
Cardiac & Cardiovascular Systems
Noriyuki Kashiyama, Robert L. Kormos, Yasumoto Matsumura, Antonio D'Amore, Shigeru Miyagawa, Yoshiki Sawa, William R. Wagner
Summary: Combining ADSCs with a cardiac patch shows improved engraftment, cardiac function, and neovascularization in a rat ischemic cardiomyopathy model.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Food Science & Technology
Shanshan Chen, Minglu Xu, Min Zhou, Yingxin He, Yongchun Li, Hui Lang, Xuliang Wei, Lijie Yan, Hongde Xu
Summary: The study found that Hibiscus manihot may reduce obesity in mice by changing the composition of the gut microbiota and activating UCP1 to increase thermogenesis of brown fat, making it a potential drug for treating obesity.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Surgery
Meishu Zhu, Meihui Zhu, Xiaoling Wu, Meiquan Xu, Kunwu Fan, Jinming Wang, Liyong Zhang, Meifang Yin, Jun Wu, Zhixiang Zhu, Guang Yang
Summary: The study found that adding PADM can reduce fat liquefaction and increase fat survival rate by increasing macrophage infiltration, extracellular matrix regeneration, and revascularization.
AESTHETIC PLASTIC SURGERY
(2021)
Article
Multidisciplinary Sciences
Ning Jiang, Zhe Wang, Xiangying Guo, Zifu Peng, Yimin He, Qian Wang, Huaduo Wu, Yunlong Cui
Summary: Endurance exercise can significantly reduce obesity induced by high fat diet by regulating related genes and activating mitochondrial function to improve body fat index.
SCIENTIFIC REPORTS
(2023)
Article
Surgery
Tianjia Zhang, Jiewen Dai, Yuting Xu, Liya Yu, Xudong Wang
Summary: Adding liquid phase concentrated growth factor to autologous fat can reduce fat absorption, especially in the early stages, without complications. The effect is improved with increased CGF. The most suitable ratio of LPCGF to fat is 1:8 for improving autologous fat graft survival.
AESTHETIC PLASTIC SURGERY
(2021)
Article
Nutrition & Dietetics
Ryota Matsui, Noriyuki Inaki, Toshikatsu Tsuji, Yoji Kokura, Ryo Momosaki
Summary: This study found that high visceral fat mass, while increasing the risk of severe complications after radical gastrectomy for gastric cancer, also improves the long-term prognosis of patients.
Article
Pharmacology & Pharmacy
Jessica Latorre, Aina Lluch, Francisco J. Ortega, Aleix Gavalda-Navarro, Ferran Comas, Samantha Moron-Ros, Amaia Rodriguez, Sara Becerril, Francesc Villarroya, Gema Fruhbeck, Wifredo Ricart, Marta Giralt, Jose Manuel Fernandez-Real, Jose Maria Moreno-Navarrete
Summary: The study found that lysozyme is highly expressed in adipose tissue of obese individuals, associated with chronic inflammation, adipose tissue inflammation, and metabolic disturbances. Knocking down the lysozyme gene in experimental models improved adipose tissue inflammation and reduced weight gain.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Oncology
Giulio Alessandri, Augusto Pessina, Rita Paroni, Luisa Bercich, Francesca Paino, Michele Dei Cas, Moris Cadei, Arnaldo Caruso, Marco Schiariti, Francesco Restelli, Offer Zeira, Carlo Tremolada, Nazario Portolani
Summary: The study indicates that microfragmented adipose tissue and its devitalized counterpart have the potential to be effective natural scaffolds for delivering anti-cancer drugs, inhibiting tumor growth relapse, particularly showing promise in treating advanced hepatocellular carcinoma.
Article
Endocrinology & Metabolism
Antu Antony, Zeqin Lian, Xiaoyuan Dai Perrard, Jerry Perrard, Hua Liu, Aaron R. Cox, Pradip Saha, Lothar Hennighausen, Sean M. Hartig, Christie M. Ballantyne, Huaizhu Wu
Summary: This study investigated the role of Stat1 in obesity-induced MDC polarization and inflammation, using mice with specific knockout of Stat1 in MDCs. The results showed that Stat1 in MDCs plays a crucial role in promoting M1-like polarization, contributing to AT inflammation, insulin resistance, and metabolic dysfunctions in obese mice.
Article
Immunology
Johannes Hoch, Niklas Burkhard, Shanshan Zhang, Marina Rieder, Timoteo Marchini, Vincent Geest, Krystin Krauel, Timm Zahn, Nicolas Schommer, Muataz Ali Hamad, Carolina Bauer, Nadine Gauchel, Daniela Stallmann, Claus Normann, Dennis Wolf, Ruediger Eberhard Scharf, Daniel Duerschmied, Nancy Schanze
Summary: This study found that deficiency of the serotonin transporter (SERT) is associated with metabolic derangements in mice. High-fat diet feeding in SERT-deficient mice resulted in enhanced insulin resistance, liver steatosis, and adipose tissue inflammation. These findings suggest that SERT deficiency may contribute to altered inflammatory processes.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Engineering, Biomedical
Camille Le Guilcher, Gregory Merlen, Alessandra Dellaquila, Marie-Noeurolle Labour, Rachida Aid, Thierry Tordjmann, Didier Letourneur, Teresa Simon-Yarza
Summary: Porous pullulan-dextran hydrogel can be used to self-assemble hepatocytes and biliary-like cells into functional 3D microtissues, showing potential value in clinical applications.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Multidisciplinary
Yan-yan Yu, Shi-chao Cui, Tian-nan Zheng, Hai-jian Ma, Zhi-fu Xie, Hao-wen Jiang, Yu-feng Li, Ke-xin Zhu, Cheng-gang Huang, Jia Li, Jing-ya Li
Summary: This study demonstrated that ZGY treatment can improve insulin resistance in obese mice by reducing adipose tissue inflammation and macrophage infiltration. ZGY not only inhibits inflammatory responses in macrophages and adipocytes, but also disrupts the crosstalk between them, improving adipocyte insulin resistance. The beneficial effects of ZGY may be mediated through inactivation of the IKK/NF-kappa B and JNK inflammatory signaling pathways in adipocytes.
ACTA PHARMACOLOGICA SINICA
(2021)
Article
Cell & Tissue Engineering
Zifeng Zeng, Liwei Xu, Yu Xu, Yongsheng Ruan, Deshen Liu, Jiale Li, Chuanjie Niu, Shaoyi Zheng, Pengyu Zhou, Zezhou Xiao
Summary: The study demonstrates that the combination of BMSCs-CM treatment and EVHP can alleviate warm I/R injury in DCD hearts by reducing oxidative stress, inflammatory response, and apoptosis levels, which in turn might help alleviate the shortage of donor hearts.
STEM CELLS INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Saher Hamed, Jonia Alshiek, Anat Aharon, Benjamin Brenner, Ariel Roguin
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2010)
Editorial Material
Medicine, Research & Experimental
Saher Hamed
BIOMARKERS IN MEDICINE
(2011)
Article
Cardiac & Cardiovascular Systems
Saher Hamed, Benjamin Brenner, Anat Aharon, Deeb Daoud, Ariel Roguin
CARDIOVASCULAR DIABETOLOGY
(2009)
Review
Cardiac & Cardiovascular Systems
Saher Hamed, Benjamin Brenner, Ariel Roguin
CARDIOVASCULAR RESEARCH
(2011)
Article
Endocrinology & Metabolism
Mogher Khamaisi, Rachel Dahan, Saher Hamed, Zaid Abassi, Samuel N. Heyman, Itamar Raz
Article
Dermatology
Saher Hamed, Yehuda Ullmann, Muhannad Masoud, Elias Hellou, Ziad Khamaysi, Luc Teot
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2010)
Article
Dermatology
Saher Hamed, Yehuda Ullmann, Dana Egozi, Essam Daod, Elias Hellou, Manal Ashkar, Amos Gilhar, Luc Teot
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2011)
Article
Surgery
Saher Hamed, Ohad Ben-Nun, Dana Egozi, Aviad Keren, Nastya Malyarova, Danny Kruchevsky, Amos Gilhar, Yehuda Ullmann
PLASTIC AND RECONSTRUCTIVE SURGERY
(2012)
Article
Surgery
Saher Hamed, Dana Egozi, Hanna Dawood, Aviad Keren, Danny Kruchevsky, Ohad Ben-Nun, Amos Gilhar, Benjamin Brenner, Yehuda Ullmann
PLASTIC AND RECONSTRUCTIVE SURGERY
(2013)
Article
Hematology
Saher Hamed, Benjamin Brenner, Zaid Abassi, Anat Aharon, Deeb Daoud, Ariel Roguin
THROMBOSIS RESEARCH
(2010)
Article
Cell Biology
Saher Hamed, Charles L. Bennett, Claire Demiot, Yehuda Ullmann, Luc Teot, Alexis Desmouliere
WOUND REPAIR AND REGENERATION
(2014)
Article
Dermatology
Saher Hamed, Mark Belokopytov, Yehuda Ullmann, Muhammad Safadi, Yafit Stark, Aziz Shoufani, Sadanori Akita, Paul Y. Liu, Luc Teot
ADVANCES IN WOUND CARE
(2019)
Article
Geriatrics & Gerontology
Saher Hamed, Yehuda Ullmann, Mark Belokopytov, Aziz Shoufani, Hoda Kabha, Suher Masri, Zeev Feldbrin, Leonid Kogan, Danny Kruchevsky, Roger Najjar, Paul Y. Liu, Jean-Charles Kerihuel, Sadanori Akita, Luc Teot
Summary: Topical erythropoietin (EPO) has shown promising results in promoting the healing of diabetic foot ulcers (DFUs) based on a randomized controlled trial. The study found that DFUs treated with topical EPO had a significantly higher rate of ulcer closure and smaller ulcer area compared to standard-of-care treatment alone.
REJUVENATION RESEARCH
(2021)
Article
Endocrinology & Metabolism
Saher Hamed, Yehuda Ullmann, Dana Egozi, Aviad Keren, Essam Daod, Omer Anis, Hoda Kabha, Mark Belokopytov, Manal Ashkar, Rona Shofti, Asaph Zaretsky, Michal Schlesinger, Luc Teot, Paul Y. Liu