Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737

Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks

(2014) Teresa A. Colvin et al.   CANCER RESEARCH

Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

(2014) Bruno Christian Koehler et al.   PLoS One

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures

(2013) Elisa Carra et al.   CELL CYCLE

The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737

(2013) Mariana Boiani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways

(2013) F Rapino et al.   ONCOGENE

BAG3 Protein Is Overexpressed in Human Glioblastoma and Is a Potential Target for Therapy

(2011) Michelina Festa et al.   AMERICAN JOURNAL OF PATHOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1

(2011) S Huber et al.   LEUKEMIA

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum

(2010) J Lian et al.   CELL DEATH AND DIFFERENTIATION

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

(2010) Feifan Zhou et al.   FEBS Journal

KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter

(2010) Young Ju Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bcl-2 Homology Domain 3 Mimetic Gossypol Induces Both Beclin 1-dependent and Beclin 1-independent Cytoprotective Autophagy in Cancer Cells

(2010) Ping Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pan-Bcl-2 Inhibitor (-)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma

(2010) V. Voss et al.   MOLECULAR CANCER RESEARCH

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mimicking the BH3 domain to kill cancer cells

(2009) T Ni Chonghaile et al.   ONCOGENE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

BCL-2 family antagonists for cancer therapy

(2008) Guillaume Lessene et al.   NATURE REVIEWS DRUG DISCOVERY

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

(2008) K E Tagscherer et al.   ONCOGENE