Rettransgenic mouse model of spontaneous skin melanoma: focus on regulatory T cells

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

(2012) Lawrence N Kwong et al.   NATURE MEDICINE

What are regulatory T cells (Treg) regulating in cancer and why?

(2012) Theresa L. Whiteside   SEMINARS IN CANCER BIOLOGY

Basic principles of tumor-associated regulatory T cell biology

(2012) Peter A. Savage et al.   TRENDS IN IMMUNOLOGY

T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma

(2012) Oliver Abschuetz et al.   Cancers

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

(2011) A. V. Sauer et al.   BLOOD

Regulatory dendritic cells: New targets for cancer immunotherapy

(2011) Michael R. Shurin et al.   CANCER BIOLOGY & THERAPY

Novel insights into the molecular mechanisms of HLA class I abnormalities

(2011) Barbara Seliger   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?

(2011) Arcadi Cipponi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

T Cells Contribute to Tumor Progression by Favoring Pro-Tumoral Properties of Intra-Tumoral Myeloid Cells in a Mouse Model for Spontaneous Melanoma

(2011) Renée Lengagne et al.   PLoS One

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma

(2011) Andrea J. McKinney et al.   Chinese Journal of Cancer

Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign

(2010) Isabel Poschke et al.   CANCER RESEARCH

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Epidemiology of invasive cutaneous melanoma

(2009) R. M. MacKie et al.   ANNALS OF ONCOLOGY

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Activation of p38 Mitogen-Activated Protein Kinase Drives Dendritic Cells to Become Tolerogenic in Ret Transgenic Mice Spontaneously Developing Melanoma

(2009) F. Zhao et al.   CLINICAL CANCER RESEARCH

Diagnosis and treatment of melanoma: European consensus-based interdisciplinary guideline

(2009) Claus Garbe et al.   EUROPEAN JOURNAL OF CANCER

Mouse models for melanoma: a personal perspective

(2009) Jürgen C. Becker et al.   EXPERIMENTAL DERMATOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Skin Melanoma Development in ret Transgenic Mice Despite the Depletion of CD25+Foxp3+ Regulatory T Cells in Lymphoid Organs

(2009) S. Kimpfler et al.   JOURNAL OF IMMUNOLOGY

Understanding Melanoma Signaling Networks as the Basis for Molecular Targeted Therapy

(2009) Keiran S.M. Smalley   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Recent advances and hurdles in melanoma immunotherapy

(2009) Camilla Jandus et al.   Pigment Cell & Melanoma Research

Melanoma-Specific Memory T Cells Are Functionally Active in Ret Transgenic Mice without Macroscopic Tumors

(2008) V. Umansky et al.   CANCER RESEARCH

Immune surveillance: a balance between protumor and antitumor immunity

(2008) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN GENETICS & DEVELOPMENT

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology