Activating Autoantibodies and Cardiovascular Disease

Angiotensin Receptor Agonistic Autoantibody-Mediated Soluble Fms-Like Tyrosine Kinase-1 Induction Contributes to Impaired Adrenal Vasculature and Decreased Aldosterone Production in Preeclampsia

(2013) Athar H. Siddiqui et al.   HYPERTENSION

Structure of the Human Angiotensin II Type 1 (AT1) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode

(2013) Dany Fillion et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats

(2012) Sarah Richards Novotny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy

(2012) Pushpinder Dhillion et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Autoantibody-Mediated Complement C3a Receptor Activation Contributes to the Pathogenesis of Preeclampsia

(2012) Wei Wang et al.   HYPERTENSION

Elevation of Angiotensin-II Type-1-Receptor Autoantibodies Titer in Primary Aldosteronism as a Result of Aldosterone-Producing Adenoma

(2012) Giacomo Rossitto et al.   HYPERTENSION

Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia

(2011) Ravi Thadhani et al.   CIRCULATION

Angiotensin II Type 1 Receptor Antibodies and Increased Angiotensin II Sensitivity in Pregnant Rats

(2011) Katrin Wenzel et al.   HYPERTENSION

Adrenergic Cardiovascular Control Before and After Removal of Stimulatory α-1 Adrenoreceptor Antibodies

(2011) Christoph Schroeder et al.   HYPERTENSION

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis

(2010) G. Riemekasten et al.   ANNALS OF THE RHEUMATIC DISEASES

Angiotensin Receptor Agonistic Autoantibody–Mediated Tumor Necrosis Factor-α Induction Contributes to Increased Soluble Endoglin Production in Preeclampsia

(2010) Cissy Chenyi Zhou et al.   CIRCULATION

Cardiac β1-adrenoceptor autoantibodies in human heart disease: rationale and design of theEtiology,Titre-Course, andSurvival (ETiCS) Study

(2010) Nikolas Deubner et al.   EUROPEAN JOURNAL OF HEART FAILURE

Autoantibody-Mediated Angiotensin Receptor Activation Contributes to Preeclampsia Through Tumor Necrosis Factor-α Signaling

(2010) Roxanna A. Irani et al.   HYPERTENSION

α1A-Adrenergic Receptor-Directed Autoimmunity Induces Left Ventricular Damage and Diastolic Dysfunction in Rats

(2010) Katrin Wenzel et al.   PLoS One

Angiotensin Receptor Agonistic Autoantibody Is Highly Prevalent in Preeclampsia

(2009) Athar H. Siddiqui et al.   HYPERTENSION

The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia

(2009) Roxanna A. Irani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoantibody From Women With Preeclampsia Induces Soluble Fms-Like Tyrosine Kinase-1 Production via Angiotensin Type 1 Receptor and Calcineurin/Nuclear Factor of Activated T-Cells Signaling

(2008) Cissy Chenyi Zhou et al.   HYPERTENSION

Prevalence of Agonistic Autoantibodies Against the Angiotensin II Type 1 Receptor and Soluble fms-Like Tyrosine Kinase 1 in a Gestational Age–Matched Case Study

(2008) Florian Herse et al.   HYPERTENSION

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

(2008) Cissy C Zhou et al.   NATURE MEDICINE

Potential Relevance of α1-Adrenergic Receptor Autoantibodies in Refractory Hypertension

(2008) Katrin Wenzel et al.   PLoS One