Bovine β-defensin gene family: opportunities to improve animal health?

Cellular Response to Trypanosoma cruzi Infection Induces Secretion of Defensin α-1, Which Damages the Flagellum, Neutralizes Trypanosome Motility, and Inhibits Infection

(2013) Candice A. Johnson et al.   INFECTION AND IMMUNITY

Livestock Origin for a Human Pandemic Clone of Community-Associated Methicillin-Resistant Staphylococcus aureus

(2013) L. E. Spoor et al.   mBio

Expression of Beta Defensin 2 in Experimental Pulmonary Tuberculosis: Tentative Approach for Vaccine Development

(2012) Bruno Rivas-Santiago et al.   ARCHIVES OF MEDICAL RESEARCH

Genome-level identification, gene expression, and comparative analysis of porcine ß-defensin genes

(2012) Min-Kyeung Choi et al.   BMC GENETICS

Expression of antimicrobial peptides by bovine endothelial cells

(2012) Nayeli Alva-Murillo et al.   CELLULAR IMMUNOLOGY

Copy number variation of individual cattle genomes using next-generation sequencing

(2012) D. M. Bickhart et al.   GENOME RESEARCH

Hypoxia Triggers the Expression of Human   Defensin 2 and Antimicrobial Activity against Mycobacterium tuberculosis in Human Macrophages

(2012) D. Nickel et al.   JOURNAL OF IMMUNOLOGY

 -defensin Genomic Copy Number Is Associated With HIV Load and Immune Reconstitution in Sub-Saharan Africans

(2012) R. J. Hardwick et al.   JOURNAL OF INFECTIOUS DISEASES

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

Digested and Fermented Green Kiwifruit Increases Human β-Defensin 1 and 2 Production In vitro

(2012) Kerry L. Bentley-Hewitt et al.   PLANT FOODS FOR HUMAN NUTRITION

β-defensin 2 as an Adjuvant Promotes Anti-Melanoma Immune Responses and Inhibits the Growth of Implanted Murine Melanoma In Vivo

(2012) Han-fang Mei et al.   PLoS One

Next Generation Sequencing to Define Prokaryotic and Fungal Diversity in the Bovine Rumen

(2012) Derrick E. Fouts et al.   PLoS One

The postpartum endometrial inflammatory response: a normal physiological event with potential implications for bovine fertility

(2012) Aspinas Chapwanya et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Endometrial epithelial cells are potent producers of tracheal antimicrobial peptide and serum amyloid A3 gene expression in response to E. coli stimulation

(2012) Aspinas Chapwanya et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

A Species-Specific Cluster of Defensin-Like Genes Encodes Diffusible Pollen Tube Attractants in Arabidopsis

(2012) Hidenori Takeuchi et al.   PLOS BIOLOGY

Multifunctional cationic host defence peptides and their clinical applications

(2011) Amy T. Y. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Induction of β-defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis

(2011) C. E. Rivas-Santiago et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

(2011) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A worldwide analysis of beta-defensin copy number variation suggests recent selection of a high-expressing DEFB103 gene copy in East Asia

(2011) Robert J. Hardwick et al.   HUMAN MUTATION

The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells

(2011) Jun Yang et al.   IMMUNOGENETICS

Reproductive tissue-specific expression profiling and genetic variation across a 19 gene bovine β-defensin cluster

(2011) Fernando Narciandi et al.   IMMUNOGENETICS

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation

(2011) Miriam Wilmes et al.   NATURAL PRODUCT REPORTS

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Butyrate Enhances Disease Resistance of Chickens by Inducing Antimicrobial Host Defense Peptide Gene Expression

(2011) Lakshmi T. Sunkara et al.   PLoS One

Modulatory Effects of Bovine Seminal Plasma on Uterine Inflammatory Processes

(2011) S Aloé et al.   REPRODUCTION IN DOMESTIC ANIMALS

A Common Mutation in the Defensin DEFB126 Causes Impaired Sperm Function and Subfertility

(2011) T. L. Tollner et al.   Science Translational Medicine

Enhancing the role of veterinary vaccines reducing zoonotic diseases of humans: Linking systems biology with vaccine development

(2011) L. Garry Adams et al.   VACCINE

Editorial: β-Defensins and Crohn's Disease: Confusion From Counting Copies

(2010) Edward J Hollox   AMERICAN JOURNAL OF GASTROENTEROLOGY

Lipopolysaccharide-Induced Epididymitis Disrupts Epididymal Beta-Defensin Expression and Inhibits Sperm Motility in Rats1

(2010) Dongmei Cao et al.   BIOLOGY OF REPRODUCTION

The epididymis-specific antimicrobial peptide β-defensin 15 is required for sperm motility and male fertility in the rat (Rattus norvegicus)

(2010) Yue Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human  -Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

(2010) V. Sass et al.   INFECTION AND IMMUNITY

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis

(2010) Ge Jin et al.   PLoS One

Antibacterial and Antiviral Roles of a Fish β-Defensin Expressed Both in Pituitary and Testis

(2010) Jun-Yan Jin et al.   PLoS One

Experimental Staphylococcus aureus infection of the mammary gland induces region-specific changes in innate immune gene expression

(2010) Cormac J. Whelehan et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The variant red coat colour phenotype of Holstein cattle maps to BTA27

(2009) D. L. Dreger et al.   ANIMAL GENETICS

Defining Postpartum Uterine Disease and the Mechanisms of Infection and Immunity in the Female Reproductive Tract in Cattle1

(2009) I. Martin Sheldon et al.   BIOLOGY OF REPRODUCTION

The adult boar testicular and epididymal transcriptomes

(2009) Benoît Guyonnet et al.   BMC GENOMICS

The repertoire of equine intestinal α-defensins

(2009) Oliver Bruhn et al.   BMC GENOMICS

Copy number variation of beta-defensins and relevance to disease

(2009) E.J. Hollox   CYTOGENETIC AND GENOME RESEARCH

Defensins as anti-inflammatory compounds and mucosal adjuvants

(2009) Karl G Kohlgraf et al.   Future Microbiology

Existence of functional lingual antimicrobial peptide in bovine milk

(2009) N. Isobe et al.   JOURNAL OF DAIRY SCIENCE

Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle

(2009) Kieran G. Meade et al.   MOLECULAR IMMUNOLOGY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Defensins keep the peace too

(2009) Alfredo Menendez et al.   NATURE IMMUNOLOGY

Livestock infectious diseases and zoonoses

(2009) F. M. Tomley et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Expression of tracheal antimicrobial peptide in bovine mammary epithelial cells

(2009) Joel E. López-Meza et al.   RESEARCH IN VETERINARY SCIENCE

Molecular and Evolutionary History of Melanism in North American Gray Wolves

(2009) T. M. Anderson et al.   SCIENCE

The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

(2009) et al.   SCIENCE

Histopathological and molecular evaluation of Holstein-Friesian cows postpartum: Toward an improved understanding of uterine innate immunity

(2009) Aspinas Chapwanya et al.   THERIOGENOLOGY

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Directional and balancing selection in human beta-defensins

(2008) Edward J Hollox et al.   BMC EVOLUTIONARY BIOLOGY

Differential antimicrobial peptide gene expression patterns during early chicken embryological development

(2008) Kieran G. Meade et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Defensins and the convergent evolution of platypus and reptile venom genes

(2008) C. M. Whittington et al.   GENOME RESEARCH

Macaque sperm coating protein DEFB126 facilitates sperm penetration of cervical mucus

(2008) T. L. Tollner et al.   HUMAN REPRODUCTION

Evolution, expression and effectiveness in a cluster of novel bovine β-defensins

(2008) Paul Cormican et al.   IMMUNOGENETICS

Directed alteration of a novel bovine β-defensin to improve antimicrobial efficacy against methicillin-resistant Staphylococcus aureus (MRSA)

(2008) Kieran G. Meade et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Identification of novel host defense peptides and the absence of α-defensins in the bovine genome

(2008) Christopher D. Fjell et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Toll-like receptor and antimicrobial peptide expression in the bovine endometrium

(2008) Darren Davies et al.   Reproductive Biology and Endocrinology

Uterine diseases in cattle after parturition

(2008) I. Martin Sheldon et al.   VETERINARY JOURNAL

Beta-Defensin 126 on the Surface of Macaque Sperm Mediates Attachment of Sperm to Oviductal Epithelia1

(2007) Theodore L. Tollner et al.   BIOLOGY OF REPRODUCTION

Host defence peptides—a bridge between the innate and adaptive immune responses

(2007) Robert P. Allaker   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE