Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: A coarse-grained molecular dynamics study

The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition

(2010) Lucie Khemtémourian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Liposome Damage and Modeling of Fragments of Human Islet Amyloid Polypeptide (IAPP) Support a Two-Step Model of Membrane Destruction

(2010) Deborah L. Heyl et al.   International Journal of Peptide Research and Therapeutics

Polarizable Water Model for the Coarse-Grained MARTINI Force Field

(2010) Semen O. Yesylevskyy et al.   PLoS Computational Biology

Cholesterol Modulates the Interaction of β-Amyloid Peptide with Lipid Bilayers

(2009) Liming Qiu et al.   BIOPHYSICAL JOURNAL

Membrane permeabilization by Islet Amyloid Polypeptide

(2009) Maarten F.M. Engel   CHEMISTRY AND PHYSICS OF LIPIDS

Membrane poration by antimicrobial peptides combining atomistic and coarse-grained descriptions

(2009) Andrzej J. Rzepiela et al.   FARADAY DISCUSSIONS

Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol

(2009) Diana Radovan et al.   FEBS LETTERS

Cholesterol Regulates Glucose-stimulated Insulin Secretion through Phosphatidylinositol 4,5-Bisphosphate

(2009) Mingming Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic α-Helix Structure of Micelle-bound Human Amylin

(2009) Sharadrao M. Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly dynamics of two-β sheets revealed by molecular dynamics simulations

(2009) Weixin Xu et al.   JOURNAL OF CHEMICAL PHYSICS

Helix Stabilization Precedes Aqueous and Bilayer-Catalyzed Fiber Formation in Islet Amyloid Polypeptide

(2009) Jessica A. Williamson et al.   JOURNAL OF MOLECULAR BIOLOGY

Cholesterol Regulates Assembly of Human Islet Amyloid Polypeptide on Model Membranes

(2009) Won-Jin Cho et al.   JOURNAL OF MOLECULAR BIOLOGY

Thermodynamic Analysis of the Effect of Cholesterol on Dipalmitoylphosphatidylcholine Lipid Membranes

(2009) W. F. Drew Bennett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of cholesterol on the structure of a phospholipid bilayer

(2009) F. de Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloidogenesis Abolished by Proline Substitutions but Enhanced by Lipid Binding

(2009) Ping Jiang et al.   PLoS Computational Biology

Calcium-activated membrane interaction of the islet amyloid polypeptide: Implications in the pathogenesis of type II diabetes mellitus

(2008) Michele F.M. Sciacca et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Coarse-grained simulation: a high-throughput computational approach to membrane proteins

(2008) Mark S.P. Sansom et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structures of Rat and Human Islet Amyloid Polypeptide IAPP1−19in Micelles by NMR Spectroscopy†

(2008) Ravi Prakash Reddy Nanga et al.   BIOCHEMISTRY

A Single Mutation in the Nonamyloidogenic Region of Islet Amyloid Polypeptide Greatly Reduces Toxicity†

(2008) Jeffrey R. Brender et al.   BIOCHEMISTRY

Interaction between Alzheimer's Aβ(25–35) peptide and phospholipid bilayers: The role of cholesterol

(2008) Gerardino D'Errico et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Toroidal pores formed by antimicrobial peptides show significant disorder

(2008) Durba Sengupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mechanosensitive Membrane Channels in Action

(2008) Serge Yefimov et al.   BIOPHYSICAL JOURNAL

Melittin-Lipid Bilayer Interactions and the Role of Cholesterol

(2008) Per Wessman et al.   BIOPHYSICAL JOURNAL

Protein misfolding and disease: from the test tube to the organism

(2008) Leila M Luheshi et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer

(2008) Rakez Kayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of α-Helical Membrane-bound Human Islet Amyloid Polypeptide and Its Implications for Membrane-mediated Misfolding

(2008) Melania Apostolidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

Cholesterol in islet dysfunction and type 2 diabetes

(2008) Liam R. Brunham et al.   JOURNAL OF CLINICAL INVESTIGATION

GridMAT-MD: A grid-based membrane analysis tool for use with molecular dynamics

(2008) William J. Allen et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Coarse-Grained Molecular Dynamics Studies of the Concentration and Size Dependence of Fifth- and Seventh-Generation PAMAM Dendrimers on Pore Formation in DMPC Bilayer

(2008) Hwankyu Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Amyloid Fiber Formation and Membrane Disruption are Separate Processes Localized in Two Distinct Regions of IAPP, the Type-2-Diabetes-Related Peptide

(2008) Jeffrey R. Brender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA and lipid bilayers: self-assembly and insertion

(2008) S. Khalid et al.   Journal of the Royal Society Interface

Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly

(2008) Kathryn A. Scott et al.   STRUCTURE

New structures help the modeling of toxic amyloidß ion channels

(2008) Hyunbum Jang et al.   TRENDS IN BIOCHEMICAL SCIENCES