Navigating the cell: how motors overcome roadblocks and traffic jams to efficiently transport cargo

Super-Resolution Microscopy: Going Live and Going Fast

(2013) Melike Lakadamyali   CHEMPHYSCHEM

Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin

(2013) Lukas C. Kapitein et al.   CURRENT BIOLOGY

Local Cytoskeletal and Organelle Interactions Impact Molecular-Motor-Driven Early Endosomal Trafficking

(2013) Allison L. Zajac et al.   CURRENT BIOLOGY

Functions and mechanics of dynein motor proteins

(2013) Anthony J. Roberts et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Filament-Filament Switching Can Be Regulated by Separation Between Filaments Together with Cargo Motor Number

(2013) Robert P. Erickson et al.   PLoS One

Correlative live-cell and superresolution microscopy reveals cargo transport dynamics at microtubule intersections

(2013) Štefan Bálint et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

(2012) Christina Leidel et al.   BIOPHYSICAL JOURNAL

Microtubule length dependence of motor traffic in cells

(2012) Yunxin Zhang   EUROPEAN PHYSICAL JOURNAL E

Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system

(2012) Nicholas M. Kanaan et al.   EXPERIMENTAL NEUROLOGY

Disruption of Axonal Transport in Motor Neuron Diseases

(2012) Kensuke Ikenaka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Torque Generation of Kinesin Motors Is Governed by the Stability of the Neck Domain

(2012) Melanie Brunnbauer et al.   MOLECULAR CELL

Tuning the “Roadblock” Effect in Kinesin-Based Transport

(2012) Claudia Schmidt et al.   NANO LETTERS

Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors

(2012) K. Furuta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Motor transport of self-assembled cargos in crowded environments

(2012) L. Conway et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular crowding creates traffic jams of kinesin motors on microtubules

(2012) C. Leduc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis

(2012) P. Marinkovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tug-of-War in Motor Protein Ensembles Revealed with a Programmable DNA Origami Scaffold

(2012) N. D. Derr et al.   SCIENCE

Rotational dynamics of cargos at pauses during axonal transport

(2012) Yan Gu et al.   Nature Communications

Crowding of Molecular Motors Determines Microtubule Depolymerization

(2011) Louis Reese et al.   BIOPHYSICAL JOURNAL

Development of target-specific multimodality imaging agent by using hollow manganese oxide nanoparticles as a platform

(2011) Tae-Lin Ha et al.   CHEMICAL COMMUNICATIONS

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

(2011) Catarina P. Samora et al.   NATURE CELL BIOLOGY

Moving into the cell: single-molecule studies of molecular motors in complex environments

(2011) Claudia Veigel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A universal pathway for kinesin stepping

(2011) Bason E Clancy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neuronal intracellular transport and neurodegenerative disease

(2011) N. P. Staff et al.   NEUROLOGY

Influence of Gold Nanorod Geometry on Optical Response

(2010) Anthony S. Stender et al.   ACS Nano

Structural and Functional Insights into the Myosin Motor Mechanism

(2010) H. Lee Sweeney et al.   Annual Review of Biophysics

Probing Intracellular Motor Protein Activity Using an Inducible Cargo Trafficking Assay

(2010) Lukas C. Kapitein et al.   BIOPHYSICAL JOURNAL

Breaking the Diffraction Barrier: Super-Resolution Imaging of Cells

(2010) Bo Huang et al.   CELL

Motor Number Controls Cargo Switching at Actin-Microtubule Intersections In Vitro

(2010) Harry W. Schroeder et al.   CURRENT BIOLOGY

Coordination of molecular motors: from in vitro assays to intracellular dynamics

(2010) Erika LF Holzbaur et al.   CURRENT OPINION IN CELL BIOLOGY

Resolving Rotational Motions of Nano-objects in Engineered Environments and Live Cells with Gold Nanorods and Differential Interference Contrast Microscopy

(2010) Gufeng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Super-Resolution Fluorescence Microscopy

(2009) Bo Huang et al.   Annual Review of Biochemistry

Obstacles on the Microtubule Reduce the Processivity of Kinesin-1 in a Minimal In Vitro System and in Cell Extract

(2009) Ivo A. Telley et al.   BIOPHYSICAL JOURNAL

Intracellular Transport: How Do Motors Work Together?

(2009) Roop Mallik et al.   CURRENT BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Photoactivatable fluorescent proteins for diffraction-limited and super-resolution imaging

(2009) Jennifer Lippincott-Schwartz et al.   TRENDS IN CELL BIOLOGY

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

Kinesin and Dynein-Dynactin at Intersecting Microtubules: Motor Density Affects Dynein Function

(2008) Jennifer L. Ross et al.   BIOPHYSICAL JOURNAL

Cargo transport: molecular motors navigate a complex cytoskeleton

(2008) Jennifer L Ross et al.   CURRENT OPINION IN CELL BIOLOGY

Setting up roadblocks for kinesin-1: mechanism for the selective speed control of cargo carrying microtubules

(2008) Till Korten et al.   LAB ON A CHIP

Quantum-dot-assisted characterization of microtubule rotations during cargo transport

(2008) Bert Nitzsche et al.   Nature Nanotechnology

Effects of the chemomechanical stepping cycle on the traffic of molecular motors

(2008) Stefan Klumpp et al.   PHYSICAL REVIEW E

Myosin V and Kinesin act as tethers to enhance each others' processivity

(2008) M. Y. Ali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE

Tuning Microtubule-Based Transport Through Filamentous MAPs: The Problem of Dynein

(2008) Michael Vershinin et al.   TRAFFIC