Asp120Asn mutation impairs the catalytic activity of NDM-1 metallo-β-lactamase: experimental and computational study

Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases

(2013) Sushmita D. Lahiri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism

(2013) Youngchang Kim et al.   FASEB JOURNAL

A quantum mechanics/molecular mechanics study on the hydrolysis mechanism of New Delhi metallo-β-lactamase-1

(2013) Kongkai Zhu et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

A common binding mode that may facilitate the design of novel broad-spectrum inhibitors against metallo-β-lactamases

(2013) Jiao Chen et al.   MEDICINAL CHEMISTRY RESEARCH

β-Lactamase Inhibitors: An Update

(2013) Jiao Chen et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Inhibitor Discovery of Full-Length New Delhi Metallo-β-Lactamase-1 (NDM-1)

(2013) Bingzheng Shen et al.   PLoS One

Probing the Effect of the Non-Active-Site Mutation Y229W in New Delhi Metallo-β-lactamase-1 by Site-Directed Mutagenesis, Kinetic Studies, and Molecular Dynamics Simulations

(2013) Jiao Chen et al.   PLoS One

Characterization of Purified New Delhi Metallo-β-lactamase-1

(2011) Pei W. Thomas et al.   BIOCHEMISTRY

Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism

(2011) HongMin Zhang et al.   FASEB JOURNAL

Zinc Chelation with Hydroxamate in Histone Deacetylases Modulated by Water Access to the Linker Binding Channel

(2011) Ruibo Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

(2011) Zhongjie Liang et al.   PLoS One

Current Challenges in Antimicrobial Chemotherapy

(2010) Carine Bebrone et al.   DRUGS

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

Flexibility of Catalytic Zinc Coordination in Thermolysin and HDAC8: A Born−Oppenheimer ab Initio QM/MM Molecular Dynamics Study

(2009) Ruibo Wu et al.   Journal of Chemical Theory and Computation

The Mechanisms of Catalysis by Metallo -Lactamases

(2008) Michael I. Page et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS