Molecular interactions of Alzheimer amyloid-β oligomers with neutral and negatively charged lipid bilayers

Probing Structural Features of Alzheimer’s Amyloid-β Pores in Bilayers Using Site-Specific Amino Acid Substitutions

(2012) Ricardo Capone et al.   BIOCHEMISTRY

Probing ion channel activity of human islet amyloid polypeptide (amylin)

(2012) Jun Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular Interactions of Alzheimer's Aβ Protofilaments with Lipid Membranes

(2012) Florentina Tofoleanu et al.   JOURNAL OF MOLECULAR BIOLOGY

Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel Mechanism of AD Pathology

(2012) Laura Connelly et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alzheimer Aβ peptide interactions with lipid membranes

(2012) Florentina Tofoleanu et al.   Prion

Toxic fibrillar oligomers of amyloid-  have cross-  structure

(2012) J. C. Stroud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol Promotes the Interaction of Alzheimer β-Amyloid Monomer with Lipid Bilayer

(2011) Xiang Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Dynamics Simulations Reveal the Protective Role of Cholesterol in β-Amyloid Protein-Induced Membrane Disruptions in Neuronal Membrane Mimics

(2011) Liming Qiu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular Dynamics Simulations of Low-Ordered Alzheimer β-Amyloid Oligomers from Dimer to Hexamer on Self-Assembled Monolayers

(2011) Jun Zhao et al.   LANGMUIR

Structural, morphological, and kinetic studies of β-amyloid peptide aggregation on self-assembled monolayers

(2011) Qiuming Wang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Polymorphic Structures of Alzheimer's β-Amyloid Globulomers

(2011) Xiang Yu et al.   PLoS One

Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes

(2011) Justin A. Lemkul et al.   PROTEIN SCIENCE

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

(2011) Fernando Terán Arce et al.   Soft Matter

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polymorphism in Alzheimer Aβ Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape

(2010) Yifat Miller et al.   CHEMICAL REVIEWS

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Structural Convergence Among Diverse, Toxic β-Sheet Ion Channels

(2010) Hyunbum Jang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Interactions of Aβ25−35 β-Barrel-like Oligomers with Anionic Lipid Bilayer and Resulting Membrane Leakage: An All-Atom Molecular Dynamics Study

(2010) Zhongwen Chang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alzheimer Aβ1−42Monomer Adsorbed on the Self-Assembled Monolayers

(2010) Qiuming Wang et al.   LANGMUIR

Truncated  -amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

(2010) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction Between Amyloid-β (1–42) Peptide and Phospholipid Bilayers: A Molecular Dynamics Study

(2009) Charles H. Davis et al.   BIOPHYSICAL JOURNAL

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Perturbation of membranes by the amyloid β-peptide - a molecular dynamics study

(2009) Justin A. Lemkul et al.   FEBS Journal

Structure of the Amyloid-β (1−42) Monomer Absorbed To Model Phospholipid Bilayers: A Molecular Dynamics Study

(2009) Charles H. Davis et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular Modeling of Two Distinct Triangular Oligomers in Amyloid β-protein

(2009) Jie Zheng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

K3 Fragment of Amyloidogenic β2-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis

(2009) Mirela Mustata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comparative Molecular Dynamics Study of Aβ Adsorption on the Self-Assembled Monolayers

(2009) Qiuming Wang et al.   LANGMUIR

Polymorphism of amyloid-β fibrils and its effects on human erythrocyte catalase binding

(2009) Nathaniel G.N. Milton et al.   MICRON

Amyloid-β-Induced Ion Flux in Artificial Lipid Bilayers and Neuronal Cells: Resolving a Controversy

(2009) Ricardo Capone et al.   NEUROTOXICITY RESEARCH

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble Amyloid β-Oligomers Affect Dielectric Membrane Properties by Bilayer Insertion and Domain Formation: Implications for Cell Toxicity

(2008) Gintaras Valincius et al.   BIOPHYSICAL JOURNAL

Amyloid-β Membrane Binding and Permeabilization are Distinct Processes Influenced Separately by Membrane Charge and Fluidity

(2008) Pamela T. Wong et al.   JOURNAL OF MOLECULAR BIOLOGY

Annular Structures as Intermediates in Fibril Formation of Alzheimer Aβ17−42

(2008) Jie Zheng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

(2008) Eva Y. Chi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

New structures help the modeling of toxic amyloidß ion channels

(2008) Hyunbum Jang et al.   TRENDS IN BIOCHEMICAL SCIENCES

A comparative molecular dynamics analysis of the amyloid β-peptide in a lipid bilayer

(2007) Justin A. Lemkul et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Membrane Fusogenic Activity of the Alzheimer's Peptide Aβ(1–42) Demonstrated by Small-Angle Neutron Scattering

(2007) Silvia Dante et al.   JOURNAL OF MOLECULAR BIOLOGY