Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone

Title
Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone
Authors
Keywords
Liver on chip, Acetaminophen, Amiodarone, Mitochondria, Oxygen uptake, Bioreactor
Journal
ARCHIVES OF TOXICOLOGY
Volume 90, Issue 5, Pages 1181-1191
Publisher
Springer Nature
Online
2015-06-04
DOI
10.1007/s00204-015-1537-2

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