Article
Food Science & Technology
Fahriye Seyma Ozcan, Hilal Dikmen, Nihat Ozcan, Ozlem Cetin, Mustafa Celik, Antoaneta Trendafilova
Summary: This study focused on optimizing the microwave-assisted extraction (MAE) process for extracting sesquiterpene lactones from Inula helenium roots. The results showed that MAE had higher extraction efficiency and antimicrobial activity, as well as lower energy consumption and carbon emissions compared to conventional maceration.
FOOD SCIENCE & NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Ciara-Ruth Kenny, Anna Stojakowska, Ambrose Furey, Brigid Lucey
Summary: With the increasing antimicrobial resistance worldwide, it is critical to explore alternative sources of candidate molecules. This study evaluated the antimicrobial activity of elecampane roots grown in Ireland, and identified sesquiterpene lactones as potential candidates for controlling staphylococcal infections. The geographical origin of the plant did not affect its antibacterial potency or chemical composition.
Article
Biochemical Research Methods
Luca Marzullo, Oleksandr Ochkur, Serena Orlandini, Lapo Renai, Roberto Gotti, Oleh Koshovyi, Sandra Furlanetto, Massimo Del Bubba
Summary: Quality by Design was used to develop an effective extraction method for (poly)phenolic compounds from bilberry fruits obtained from different regions of Ukraine. The method was optimized through screening matrices and response surface methodology. The optimized extraction method showed good performance and can be used for compound analysis in bilberries.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Biochemistry & Molecular Biology
Jang Hoon Kim, Yea-In Park, Mok Hur, Woo Tae Park, Youn-Ho Moon, Sung Cheol Koo, Her Yun-Chan, Ik Soo Lee, Junsoo Park
Summary: Four methoxy flavonoids were isolated from Inula britannica flower extract and showed inhibitory activity against SARS-CoV-2 3CLpro. Inhibitors 1-3 also suppressed HCoV-OC43 coronavirus proliferation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Engineering, Chemical
Ruixue Liu, Xiuling Chu, Jianqing Su, Xiang Fu, Qibin Kan, Xiaoya Wang, Xinyu Zhang
Summary: The aim of this work was to investigate enzyme-assisted ultrasonic extraction of A. senticosus flavonoids and their enrichment and antioxidant properties. An effective extraction and enrichment procedure was found, with the highest flavonoid, polyphenol, saponin contents in the 1-butanol fraction, and the highest polysaccharide content in the water fraction.
Article
Chemistry, Physical
Jiangmiao Yu, Binhui Zhang, Peiqi Long, Bo Chen, Feng Guo
Summary: This study optimized the combination of groove parameters to achieve a balance between skid-resistance performance and driving stability on concrete pavements. Experimental results showed that groove depth and spacing significantly affected the performance indicators, and optimizing groove group width could balance driving stability and durability.
Article
Electrochemistry
Chiyu Ge, Junli Zhang, Mengshuang Wang
Summary: This study adopted ultrasonic assisted and ethanol reflux method to extract total flavonoids of Hovenia spp., with three factors extracted from PCA analysis reaching an interpretation rate of 98%, and identification of each species achieved by locating the hot area of the 2D density pattern, which is simpler than using electrochemical fingerprinting.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Grazyna Kowalska, Tomasz Baj, Radoslaw Kowalski, Jolanta Szymanska
Summary: This study optimized the extraction conditions of polyphenols, flavonoids, and chlorophyll from peppermint and common nettle leaves using green chemistry. The use of glycerol-water systems resulted in higher concentrations of these active compounds compared to traditional solvents like water and ethanol. Extraction temperature was found to significantly influence the concentration of the components in the extracts.
Article
Biochemistry & Molecular Biology
Abigail Garcia-Castro, Alma Delia Roman-Gutierrez, Araceli Castaneda-Ovando, Fabiola Araceli Guzman-Ortiz
Summary: In this study, the total content of phenols and flavonoids in ungerminated and germinated barley were measured. It was found that the 7-day germination time yielded the highest total phenol and flavonoid content in Esmeralda barley, while the highest content in Perla barley was observed at 5 and 7 days of germination. Different solvents were used for extraction, and the highest extraction percentage of total phenols was obtained with methanol and ethanol, while 50% acetone recovered the highest flavonoid concentrations in Esmeralda barley and 80% methanol in Perla barley.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Biochemistry & Molecular Biology
En-Yun Wu, Wen-Jing Sun, Ying Wang, Ge-Yin Zhang, Bai-Chang Xu, Xiao-Gang Chen, Kai-Yuan Hao, Ling-Zhi He, Hong-Bin Si
Summary: Abrus cantoniensis is a Chinese herbal medicine known for its heat-clearing, detoxifying, and liver pain relieving properties. Modern pharmacological studies have shown that its flavonoids have important biological activities such as anti-inflammatory, antibacterial, and antioxidant effects. By optimizing the ultrasonic extraction process, researchers found that ATF has significant anti-inflammatory effects both in vitro and in vivo.
Review
Nutrition & Dietetics
Shuning Ding, Peipei Wang, Xi Pang, Leyin Zhang, Lihui Qian, Xinru Jia, Wenqian Chen, Shanming Ruan, Leitao Sun
Summary: This study systematically reviewed the biological functions of pure total flavonoids from Citrus maxima and its components. PTFC and its components have the potential to regulate metabolism, inhibit inflammation, suppress tumor progression, protect the intestinal barrier, and regulate intestinal microbiota. However, these effects may be influenced by factors such as fruit cultivation, picking standard, manufacturing methods, delivery system, and individual intestinal microecology. Further research is needed to enhance the effectiveness and bioavailability.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Curro Polo-Castellano, Rosa Maria Mateos, Francisco Visiedo, Miguel Palma, Gerardo F. Barbero, Marta Ferreiro-Gonzalez
Summary: Moringa oleifera Lam. is a tree with significant antioxidant properties, making the development of an optimal extraction method crucial for obtaining pharmacological products based on its bioactive compounds. Enzymatic extraction conditions were optimized using Plackett-Burman and Box-Behnken designs, with normalized areas and relative mass as response and quantification variables, respectively. Under the optimal extraction conditions, enzyme extractions were performed and evaluated for antioxidant power, total phenolic compounds, repeatability, and intermediate precision.
Article
Energy & Fuels
Sayed Rashad, Ghadir El-Chaghaby, Eder C. Lima, Glaydson Simoes dos Reis
Summary: In this study, the ultrasonic-assisted extraction of antioxidants from Ulva lactuca was optimized using a full-factorial design. The results showed that temperature and solvent were the most influential factors on the extraction process. The optimum extraction conditions were 1 hour extraction time, 50% ethanol as solvent, and 25 degrees C temperature.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Review
Biochemistry & Molecular Biology
Luis Miguel Anaya-Esparza, Edward F. Aurora-Vigo, Zuami Villagran, Ernesto Rodriguez-Lafitte, Jose Martin Ruvalcaba-Gomez, Miguel angel Solano-Cornejo, Victor Manuel Zamora-Gasga, Efigenia Montalvo-Gonzalez, Horacio Gomez-Rodriguez, Cesar Eduardo Aceves-Aldrete, Napoleon Gonzalez-Silva
Summary: Plant-based materials are a significant source of bioactive compounds, and ultrasound-assisted extraction is an advanced and sustainable method for recovering these compounds. Various experimental design methods can be used to optimize the ultrasound-assisted extraction process.
Article
Chemistry, Multidisciplinary
Leyre Sillero, Raquel Prado, Tom Welton, Jalel Labidi
Summary: Research has shown that using deep eutectic solvents as additives in extraction processes for lignocellulosic biomass can result in rich extracts of flavonoid compounds. Specifically, the mixture of choline chloride:1,4-butanediol (75 wt%) has been found to give the best results, with extracts containing the highest amount of flavonoids and exhibiting the highest antioxidant capacity. These findings confirm the ability of this DES to obtain active biomolecules for further application.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
