HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2

Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway

(2015) Qingling Li et al.   Oncotarget

High Mobility Group Box 1 Protein Is Methylated and Transported to Cytoplasm in Clear Cell Renal Cell Carcinoma

(2014) Fei Wu et al.   Asian Pacific Journal of Cancer Prevention

The Pathogenesis of Hepatocellular Carcinoma

(2014) Martha M. Kirstein et al.   DIGESTIVE DISEASES

The Association of HMGB1 Gene with the Prognosis of HCC

(2014) Jianbiao Xiao et al.   PLoS One

HMGB1 plays a critical role in vascular inflammation and lesion formation via toll-like receptor 9

(2013) Yoichiro Hirata et al.   ATHEROSCLEROSIS

Thrombomodulin's lectin-like domain reduces myocardial damage by interfering with HMGB1-mediated TLR2 signalling

(2013) Christine Herzog et al.   CARDIOVASCULAR RESEARCH

High-Mobility Group Box 1 Inhibits Gastric Ulcer Healing through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products

(2013) Yuji Nadatani et al.   PLoS One

p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

(2012) K. M. Livesey et al.   CANCER RESEARCH

High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases

(2012) Wei Yan et al.   HEPATOLOGY

Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reduced High-Mobility Group Box 1 Expression Induced by RNA Interference Inhibits the Bioactivity of Hepatocellular Carcinoma Cell Line HCCLM3

(2011) Wei Jiang et al.   DIGESTIVE DISEASES AND SCIENCES

Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer

(2011) Hitoshi Ohmori et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis—Binding Myc makes the difference

(2011) Tarik Möröy et al.   SEMINARS IN IMMUNOLOGY

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

High-Mobility Group Box 1–Mediated Matrix Metalloproteinase-9 Expression in Non–Small Cell Lung Cancer Contributes to Tumor Cell Invasiveness

(2009) Po-Len Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The expression of HMGB1 protein and its receptor RAGE in human malignant tumors

(2009) Nora Kostova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-κB signaling pathway in FRTL thyroid cells

(2008) Meng Ren et al.   ACTA PHARMACOLOGICA SINICA

Serum high mobility group box chromosomal protein 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma

(2008) B.-Q. Cheng et al.   DIGESTIVE AND LIVER DISEASE

Increased expression of high mobility group box 1 (HMGB1) is associated with progression and poor prognosis in human nasopharyngeal carcinoma

(2008) D Wu et al.   JOURNAL OF PATHOLOGY