High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Biobanking and pharmacogenomics

(2010) Catherine A McCarty et al.   PHARMACOGENOMICS

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

(2010) Mathew J. Barber et al.   PLoS One

Niacin stimulates adiponectin secretion through the GPR109A receptor

(2009) Eric P. Plaisance et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Peroxisome proliferator-activated receptor-alpha (PPARα): At the crossroads of obesity, diabetes and cardiovascular disease

(2009) Jean-Charles Fruchart   ATHEROSCLEROSIS

Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders

(2009) André J. Scheen et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women

(2009) Stefania Lamon-Fava et al.   CLINICAL ENDOCRINOLOGY

Pharmacokinetic, Pharmacodynamic, and Safety Profile of a New Cholesteryl Ester Transfer Protein Inhibitor in Healthy Human Subjects

(2009) R Wolk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men

(2009) Thomas Sudhop et al.   JOURNAL OF LIPID RESEARCH

Plasma lipoproteins: genetic influences and clinical implications

(2009) Robert A. Hegele   NATURE REVIEWS GENETICS

Premature Release of Data from Clinical Trials of Ezetimibe

(2009) Robert M. Califf et al.   NEW ENGLAND JOURNAL OF MEDICINE

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Obesity-related dyslipidemia associated withFAAH, independent of insulin response, in multigenerational families of Northern European descent

(2009) Yi Zhang et al.   PHARMACOGENOMICS

Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies

(2009) Bingshan Li et al.   PLoS Genetics

Effectiveness of Thrice Weekly Ezetimibe

(2008) Carmelo V. Venero et al.   AMERICAN JOURNAL OF CARDIOLOGY

Mechanism of Action of Niacin

(2008) Vaijinath S. Kamanna et al.   AMERICAN JOURNAL OF CARDIOLOGY

Characterization of Low-Density Lipoprotein Cholesterol-Lowering Efficacy for Atorvastatin in a Population-Based DNA Biorepository

(2008) Russell A. Wilke et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Cholesteryl Ester Transfer Protein Inhibition, High-Density Lipoprotein Raising, and Progression of Coronary Atherosclerosis

(2008) Stephen J. Nicholls et al.   CIRCULATION

Efficacy and Safety of Rimonabant for Improvement of Multiple Cardiometabolic Risk Factors in Overweight/Obese Patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program

(2008) L. Van Gaal et al.   DIABETES CARE

Safety and efficacy of ezetimibe monotherapy in 1624 primary hypercholesterolaemic patients for up to 2 years

(2008) C. A. Dujovne et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Ezetimibe monotherapy for cholesterol lowering in 2,722 people: systematic review and meta-analysis of randomized controlled trials

(2008) A. Pandor et al.   JOURNAL OF INTERNAL MEDICINE

Impact of Triglyceride Levels Beyond Low-Density Lipoprotein Cholesterol After Acute Coronary Syndrome in the PROVE IT-TIMI 22 Trial

(2008) Michael Miller et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Metabolic syndrome: from epidemiology to systems biology

(2008) Aldons J. Lusis et al.   NATURE REVIEWS GENETICS

Intensive Lipid Lowering with Simvastatin and Ezetimibe in Aortic Stenosis

(2008) Anne B. Rossebø et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Will All Americans Become Overweight or Obese? Estimating the Progression and Cost of the US Obesity Epidemic

(2008) Youfa Wang et al.   Obesity

Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index

(2008) Tes M Baye et al.   PHARMACOGENOMICS