Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction

Personalized Medicine and Opioid Analgesic Prescribing for Chronic Pain: Opportunities and Challenges

(2013) Stephen Bruehl et al.   JOURNAL OF PAIN

The genetics of the opioid system and specific drug addictions

(2012) Orna Levran et al.   HUMAN GENETICS

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

BDNF Is a Negative Modulator of Morphine Action

(2012) J. W. Koo et al.   SCIENCE

Brain-Derived Neurotrophic Factor: A Dynamic Gatekeeper of Neural Plasticity

(2012) Kiriana Cowansage et al.   Current Molecular Pharmacology

Association between polymorphisms of DRD2 and DRD4 and opioid dependence: Evidence from the current studies

(2011) Dingyan Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms

(2011) Therese M Murphy et al.   Behavioral and Brain Functions

The brain-derived neurotrophic factor is associated with alcohol dependence-related depression and antidepressant response

(2011) N. Su et al.   BRAIN RESEARCH

CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration

(2011) Myriam A. Attar et al.   EXPERIMENTAL CELL RESEARCH

Genetic association between BDNF gene polymorphisms and phobic disorders: A case–control study among mainland Han Chinese

(2011) Bing Xie et al.   JOURNAL OF AFFECTIVE DISORDERS

Susceptibility genes, social environmental risk factors and their interactions in internalizing disorders among mainland Chinese undergraduates

(2011) Xiangfei Meng et al.   JOURNAL OF AFFECTIVE DISORDERS

Influence of BDNF Variants on Diagnosis and Response to Treatment in Patients with Major Depression, Bipolar Disorder and Schizophrenia

(2011) Chi-Un Pae et al.   NEUROPSYCHOBIOLOGY

Poster Session III

(2011)   NEUROPSYCHOPHARMACOLOGY

Acute Mesenteric Infarction Associated with Atrial Fibrillation

(2011) Jia-Ming Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of genetic polymorphisms inABCB1,CYP2B6,OPRM1,ANKK1andDRD2genes on methadone therapy in Han Chinese patients

(2011) Chin-Chuan Hung et al.   PHARMACOGENOMICS

Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment

(2011) O Levran et al.   PHARMACOGENOMICS JOURNAL

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

(2011) Arun K. Shukla et al.   TRENDS IN BIOCHEMICAL SCIENCES

Clinical pharmacology of methadone for pain

(2010) O. M. S. FREDHEIM et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry

(2010) Gil Atzmon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

OPRM1 SNP (A118G): Involvement in disease development, treatment response, and animal models

(2010) Stephen D. Mague et al.   DRUG AND ALCOHOL DEPENDENCE

Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism

(2010) C. T. Correia et al.   GENES BRAIN AND BEHAVIOR

Brain-derived neurotrophic factor gene polymorphisms

(2010) Neslihan Aygun Kocabas et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

The genome-wide structure of the Jewish people

(2010) Doron M. Behar et al.   NATURE

Intronic Polymorphisms Affecting Alternative Splicing of Human Dopamine D2 Receptor Are Associated with Cocaine Abuse

(2010) Robert A Moyer et al.   NEUROPSYCHOPHARMACOLOGY

The ANKK1 Protein Associated with Addictions has Nuclear and Cytoplasmic Localization and Shows a Differential Response of Ala239Thr to Apomorphine

(2010) E. Garrido et al.   NEUROTOXICITY RESEARCH

β-Arrestin2 influences the response to methadone in opioid-dependent patients

(2010) B Oneda et al.   PHARMACOGENOMICS JOURNAL

A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human

(2010) F. Soliman et al.   SCIENCE

Association of Substance Use Disorders With Childhood Trauma but not African Genetic Heritage in an African American Cohort

(2009) Francesca Ducci et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Brain-Derived Neurotrophic Factor Haplotype Is Associated with Therapeutic Response in Obsessive-Compulsive Disorder

(2009) Eva Real et al.   BIOLOGICAL PSYCHIATRY

Stress and Addiction: A Dynamic Interplay of Genes, Environment, and Drug Intake

(2009) Rajita Sinha   BIOLOGICAL PSYCHIATRY

The ANKK1 Gene Associated with Addictions Is Expressed in Astroglial Cells and Upregulated by Apomorphine

(2009) Janet Hoenicka et al.   BIOLOGICAL PSYCHIATRY

Molecular Insights Into μ Opioid Pharmacology

(2009) Gavril W. Pasternak   CLINICAL JOURNAL OF PAIN

Heroin addiction in African Americans: a hypothesis-driven association study

(2009) O. Levran et al.   GENES BRAIN AND BEHAVIOR

Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population

(2009) Kerang Zhang et al.   JOURNAL OF NEURAL TRANSMISSION

Unknown

(2009) Chao Tian et al.   MOLECULAR MEDICINE

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene

(2009) T L Petryshen et al.   MOLECULAR PSYCHIATRY

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans

(2009) C Dong et al.   MOLECULAR PSYCHIATRY

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

Genetic Predictors of Increase in Suicidal Ideation During Antidepressant Treatment in the GENDEP Project

(2009) Nader Perroud et al.   NEUROPSYCHOPHARMACOLOGY

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution

(2009) Alexandra Doehring et al.   Pharmacogenetics and Genomics

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array

(2008) C. A. Hodgkinson et al.   ALCOHOL AND ALCOHOLISM

Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia

(2008) Alessandro Bertolino et al.   BRAIN

BDNFvariability in opioid addicts and response to methadone treatment: preliminary findings

(2008) R. de Cid et al.   GENES BRAIN AND BEHAVIOR

Genetic susceptibility to heroin addiction: a candidate gene association study

(2008) O. Levran et al.   GENES BRAIN AND BEHAVIOR

Expansion of the human μ-opioid receptor gene architecture: novel functional variants

(2008) Svetlana A. Shabalina et al.   HUMAN MOLECULAR GENETICS

ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence

(2008) Orna Levran et al.   HUMAN MOLECULAR GENETICS

Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedic patients

(2008) P. A. LENZINI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Association of dopamine and opioid receptor genetic polymorphisms with response to methadone maintenance treatment

(2008) Séverine Crettol et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

(2008) Lixiang Liu et al.   PSYCHIATRIC GENETICS

Genetic Association of Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) With Alzheimer's Disease

(2007) Zuomin Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Extensive Genotyping of the BDNF and NTRK2 Genes Define Protective Haplotypes Against Obsessive-Compulsive Disorder

(2007) Pino Alonso et al.   BIOLOGICAL PSYCHIATRY