Genetic variation in the PPARA gene is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study

PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo

(2012) Kathrin Klein et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Associations between the genotypes and phenotype of CYP3A and the lipid response to simvastatin in Chinese patients with hypercholesterolemia

(2012) Miao Hu et al.   PHARMACOGENOMICS

The Rotterdam Study: 2012 objectives and design update

(2011) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in The Rotterdam Study

(2011) Laure Elens et al.   Pharmacogenetics and Genomics

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

(2010) D Wang et al.   PHARMACOGENOMICS JOURNAL

Peroxisome proliferator-activated receptor-alpha (PPARα): At the crossroads of obesity, diabetes and cardiovascular disease

(2009) Jean-Charles Fruchart   ATHEROSCLEROSIS

Influence of genetic variation inCYP3A4andABCB1on dose decrease or switching during simvastatin and atorvastatin therapy

(2009) Matthijs L. Becker et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Association of genotypes of the CYP3A cluster with midazolam disposition in vivo

(2009) J Miao et al.   PHARMACOGENOMICS JOURNAL

Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin

(2008) Pertti J Neuvonen et al.   CLINICAL PHARMACOKINETICS

Association betweenPPARα gene polymorphisms and myocardial infarction

(2008) Wibke Reinhard et al.   CLINICAL SCIENCE

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study

(2008) JB Richards et al.   LANCET

Polymorphisms in the peroxisome proliferator activated receptor α gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians

(2007) Min-Jeong Shin et al.   ATHEROSCLEROSIS