SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis

SCN1AIVS5-91G>A polymorphism is associated with susceptibility to epilepsy but not with drug responsiveness

(2013) Ritu Kumari et al.   BIOCHIMIE

Neurological perspectives on voltage-gated sodium channels

(2012) N. Eijkelkamp et al.   BRAIN

Comprehensive analysis of the association of SCN1A gene polymorphisms with the retention rate of carbamazepine following monotherapy for new-onset focal seizures in the Chinese Han population

(2012) Bo-Ting Zhou et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Effects of SCN1A and GABA Receptor Genetic Polymorphisms on Carbamazepine Tolerability and Efficacy in Chinese Patients with Partial Seizures: 2-Year Longitudinal Clinical Follow-Up

(2012) Bo-Ting Zhou et al.   CNS Neuroscience & Therapeutics

Sodium Channel Blockers as Therapeutic Target for Treating Epilepsy: Recent Updates

(2012) Valentina Zuliani et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

SCN1A IVS5N+5 polymorphism and response to sodium valproate: a multicenter study

(2012) Batoul Sadat Haerian et al.   PHARMACOGENOMICS

A functional polymorphism in the SCN1A gene does not influence antiepileptic drug responsiveness in Italian patients with focal epilepsy

(2011) Ida Manna et al.   EPILEPSIA

The new ILAE report on terminology and concepts for organization of epileptic seizures: A clinician’s critical view and contribution

(2011) Chrysostomos P. Panayiotopoulos   EPILEPSIA

A simplified universal genomic DNA extraction protocol suitable for PCR

(2011) T.Y. Wang et al.   GENETICS AND MOLECULAR RESEARCH

Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese

(2011) Youling Guo et al.   HUMAN MOLECULAR GENETICS

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization

(2011) Chin-Chuan Hung et al.   PHARMACOGENOMICS

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Genetic factors associated with drug-resistance of epilepsy: Relevance of stratification by patient age and aetiology of epilepsy

(2010) M. Blanca Sánchez et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Differential role of sodium channelsSCN1AandSCN2Agene polymorphisms with epilepsy and multiple drug resistance in the north Indian population

(2009) Ram Lakhan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

(2009) Patrick Kwan et al.   EPILEPSIA

Gene-to-Gene Interaction between Sodium Channel-Related Genes in Determining the Risk of Antiepileptic Drug Resistance

(2009) Sin-Young Jang et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

New Developments in Antiepileptic Drug Resistance: An Integrative View

(2009) Dieter Schmidt et al.   Epilepsy Currents

Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

(2009) Chris C. A. Spencer et al.   PLoS Genetics

Association betweenSCN1Apolymorphism and carbamazepine-resistant epilepsy

(2008) Tomohide Abe et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A functional polymorphism in theSCN1Agene is not associated with carbamazepine dosages in Austrian patients with epilepsy

(2008)   EPILEPSIA

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression

(2008) Patrick Kwan et al.   Pharmacogenetics and Genomics