Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown
Authors
Keywords
-
Journal
PHARMACOGENOMICS
Volume 13, Issue 3, Pages 323-341
Publisher
Future Medicine Ltd
Online
2012-02-03
DOI
10.2217/pgs.11.178
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells
- (2011) Kristy Nguyen et al. Cell Communication and Signaling
- G Protein Coupled Receptor Kinases as Therapeutic Targets in Cardiovascular Disease
- (2011) Stephen L. Belmonte et al. CIRCULATION RESEARCH
- Cardiovascular Pharmacogenomics of Adrenergic Receptor Signaling: Clinical Implications and Future Directions
- (2011) J A Johnson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels
- (2011) Anastasios Lymperopoulos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A Polymorphism-Specific "Memory" Mechanism in the 2-Adrenergic Receptor
- (2011) A. Ahles et al. Science Signaling
- Structural insights into adrenergic receptor function and pharmacology
- (2011) Brian K. Kobilka TRENDS IN PHARMACOLOGICAL SCIENCES
- Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure
- (2010) Giuseppe Rengo et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Dynamic Changes in Lymphocyte GRK2 Levels in Cardiac Transplant Patients: A Biomarker for Left Ventricular Function
- (2010) Raphael E. Bonita et al. CTS-Clinical and Translational Science
- HK-2 Human Renal Proximal Tubule Cells as a Model for G Protein–Coupled Receptor Kinase Type 4–Mediated Dopamine 1 Receptor Uncoupling
- (2010) John J. Gildea et al. HYPERTENSION
- GRK2 as a novel gene therapy target in heart failure
- (2010) Giuseppe Rengo et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Teaching old receptors new tricks: biasing seven-transmembrane receptors
- (2010) Sudarshan Rajagopal et al. NATURE REVIEWS DRUG DISCOVERY
- Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling
- (2010) L. M. Luttrell et al. PHARMACOLOGICAL REVIEWS
- Adrenergic Signaling Polymorphisms and Their Impact on Cardiovascular Disease
- (2010) Gerald W. Dorn PHYSIOLOGICAL REVIEWS
- Insertion/deletion polymorphism in α2-adrenergic receptor gene is a genetic risk factor for sudden cardiac death
- (2009) Jari A. Laukkanen et al. AMERICAN HEART JOURNAL
- G-Protein-Coupled Receptor Kinase 4 Polymorphisms and Blood Pressure Response to Metoprolol Among African Americans: Sex-Specificity and Interactions
- (2009) V. Bhatnagar et al. AMERICAN JOURNAL OF HYPERTENSION
- L41Q polymorphism of the G protein coupled receptor kinase 5 is associated with left ventricular apical ballooning syndrome
- (2009) Letizia Spinelli et al. EUROPEAN JOURNAL OF HEART FAILURE
- GRK mythology: G-protein receptor kinases in cardiovascular disease
- (2009) Gerald W. Dorn JOURNAL OF MOLECULAR MEDICINE-JMM
- Clinical and Genetic Modifiers of Long-Term Survival in Heart Failure
- (2009) Sharon Cresci et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- -Arrestin/Ral Signaling Regulates Lysophosphatidic Acid-Mediated Migration and Invasion of Human Breast Tumor Cells
- (2009) T. T. Li et al. MOLECULAR CANCER RESEARCH
- Deficiency of a β-arrestin-2 signal complex contributes to insulin resistance
- (2009) Bing Luan et al. NATURE
- A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of β2-adrenergic receptors
- (2009) Wayne C.H. Wang et al. Pharmacogenetics and Genomics
- An adrenal -arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo
- (2009) A. Lymperopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promoter Variant in the GRK3 Gene Associated with Bipolar Disorder Alters Gene Expression
- (2008) Xianjin Zhou et al. BIOLOGICAL PSYCHIATRY
- Myocardial Adeno-Associated Virus Serotype 6–βARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure
- (2008) Giuseppe Rengo et al. CIRCULATION
- Blood Pressure and Renal Sodium Handling in Relation to Genetic Variation in the DRD1 Promoter and GRK4
- (2008) Jan A. Staessen et al. HYPERTENSION
- A GRK5 polymorphism that inhibits β-adrenergic receptor signaling is protective in heart failure
- (2008) Stephen B Liggett et al. NATURE MEDICINE
- Pharmacogenomics of G Protein-Coupled Receptor Ligands in Cardiovascular Medicine
- (2008) D. Rosskopf et al. PHARMACOLOGICAL REVIEWS
- Distinct conformational changes in -arrestin report biased agonism at seven-transmembrane receptors
- (2008) A. K. Shukla et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-1 and β-2 adrenoceptor polymorphisms: Functional importance, impact on cardiovascular diseases and drug responses
- (2007) Otto-Erich Brodde PHARMACOLOGY & THERAPEUTICS
- Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning
- (2007) Alexander R Lyon et al. Nature clinical practice. Cardiovascular medicine
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started