Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses

KRAS Mutation Testing in Colorectal Cancer

(2009) Thomas P. Plesec et al.   ADVANCES IN ANATOMIC PATHOLOGY

Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease

(2009) M. A. SMITH et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

KRAS Mutational Status as a Predictor of Epidermal Growth Factor Receptor Inhibitor Efficacy in Colorectal Cancer

(2009) Roy D Baynes et al.   AMERICAN JOURNAL OF THERAPEUTICS

Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities

(2009) Helmout Modjtahedi et al.   ANTI-CANCER DRUGS

Mammalian epoxide hydrolases in xenobiotic metabolism and signalling

(2009) Martina Decker et al.   ARCHIVES OF TOXICOLOGY

Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance

(2009) Yongjian Zhu et al.   CANCER TREATMENT REVIEWS

Metallothioneins and Platinum(II) Anti-Tumor Compounds

(2009) Markus Knipp   CURRENT MEDICINAL CHEMISTRY

A genome-wide association study of acenocoumarol maintenance dosage

(2009) Martina Teichert et al.   HUMAN MOLECULAR GENETICS

Genome-wide Interrogation of Germline Genetic Variation Associated With Treatment Response in Childhood Acute Lymphoblastic Leukemia

(2009) Jun J. Yang   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Unknown

(2009) Jing Cui et al.   MOLECULAR MEDICINE

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Origins and functional impact of copy number variation in the human genome

(2009) Donald F. Conrad et al.   NATURE

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

The impact of microRNAs and alternative splicing in pharmacogenomics

(2009) F Passetti et al.   PHARMACOGENOMICS JOURNAL

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

(2009) Fumihiko Takeuchi et al.   PLoS Genetics

Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity

(2008) Jinping Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CYP4F2 genetic variant alters required warfarin dose

(2008) M. D. Caldwell et al.   BLOOD

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

(2008) G. M. Cooper et al.   BLOOD

Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis

(2008) M. E. Sarasquete et al.   BLOOD

Cellular basis of drug-induced torsades de pointes

(2008) D M Roden   BRITISH JOURNAL OF PHARMACOLOGY

Linking Antibody Fc Domain to Endostatin Significantly Improves Endostatin Half-life and Efficacy

(2008) T.-Y. Lee et al.   CLINICAL CANCER RESEARCH

Peroxidase-Mediated Bioactivation of Hydroxylated Metabolites of Carbamazepine and Phenytoin

(2008) W. Lu et al.   DRUG METABOLISM AND DISPOSITION

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS

Evaluation of coverage variation of SNP chips for genome-wide association studies

(2008) Mingyao Li et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Modifications of human carboxylesterase for improved prodrug activation

(2008) Jason M Hatfield et al.   Expert Opinion on Drug Metabolism & Toxicology

Unknown

(2008) Chunyu Liu et al.   MOLECULAR MEDICINE

Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia

(2008) S Volpi et al.   MOLECULAR PSYCHIATRY

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of metallothionein in oncogenesis and cancer prognosis

(2008) Mie Ø. Pedersen et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: Possible mechanisms involved

(2008) Vanesa G. Martinez et al.   TOXICOLOGY IN VITRO

IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations

(2007) Sofie Haglund et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery

(2007) Kishor M. Wasan et al.   NATURE REVIEWS DRUG DISCOVERY