Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity

Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine

(2013) Fabian Müller et al.   BIOCHEMICAL PHARMACOLOGY

Carvedilol efficiently protects kidneys without affecting the antitumor efficacy of cisplatin in mice

(2013) Maria A. Carvalho Rodrigues et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Conjunctive Therapy of Cisplatin With the OCT2 Inhibitor Cimetidine: Influence on Antitumor Efficacy and Systemic Clearance

(2013) J A Sprowl et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Involvement of Carnitine/Organic Cation Transporter OCTN1/SLC22A4 in Gastrointestinal Absorption of Metformin

(2013) Noritaka Nakamichi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs)

(2013) Qing Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of genetic variants in SLC22A2 organic cation transporter 2 and SLC47A1 multidrug and toxin extrusion 1 transporter on cisplatin-induced adverse events

(2012) Kazufumi Iwata et al.   Clinical and Experimental Nephrology

Ameliorative effects of SLC22A2 gene polymorphism 808 G/T and cimetidine on cisplatin-induced nephrotoxicity in Chinese cancer patients

(2012) Jing Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Organic cation transporters OCT1 and OCT2 determine the accumulation of lamivudine in CD4 cells of HIV-infected patients

(2012) N. Jung et al.   INFECTION

Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling

(2012) Matthias B. Wittwer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carvedilol Protects Against Apoptotic Cell Death Induced by Cisplatin in Renal Tubular Epithelial Cells

(2012) M. A. Carvalho Rodrigues et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Proteins

(2011) T. Minematsu et al.   MOLECULAR CANCER THERAPEUTICS

Deficiency of Multidrug and Toxin Extrusion 1 Enhances Renal Accumulation of Paraquat and Deteriorates Kidney Injury in Mice

(2011) Qing Li et al.   MOLECULAR PHARMACEUTICS

Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity

(2010) Takanori Nakamura et al.   BIOCHEMICAL PHARMACOLOGY

Protecting Cisplatin-Induced Nephrotoxicity with Cimetidine Does Not Affect Antitumor Activity

(2010) Hiromu Katsuda et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2)

(2010) H Burger et al.   BRITISH JOURNAL OF PHARMACOLOGY

Carvedilol protects against cisplatin-induced oxidative stress, redox state unbalance and apoptosis in rat kidney mitochondria

(2010) M.A. Carvalho Rodrigues et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

(2010) Vishal S Vaidya et al.   NATURE BIOTECHNOLOGY

Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity

(2009) K K Filipski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Interaction of beta-blockers with the renal uptake transporter OCT2

(2009) I. Bachmakov et al.   DIABETES OBESITY & METABOLISM

Validation of putative genomic biomarkers of nephrotoxicity in rats

(2008) Er-Jia Wang et al.   TOXICOLOGY