Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions

A Population Pharmacokinetic-Pharmacogenetic Analysis of Atazanavir

(2012) Deidre A. Kile et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

(2012) Maria Karlgren et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atazanavir Metabolism According to CYP3A5 Status: An In Vitro-In Vivo Assessment

(2010) M. F. Wempe et al.   DRUG METABOLISM AND DISPOSITION

Significance and Regional Dependency of Peptide Transporter (PEPT) 1 in the Intestinal Permeability of Glycylsarcosine: In Situ Single-Pass Perfusion Studies in Wild-Type and Pept1 Knockout Mice

(2010) D. Jappar et al.   DRUG METABOLISM AND DISPOSITION

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

(2010) W. F. W. Bierman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

pH Dependence of Organic Anion-Transporting Polypeptide 2B1 in Caco-2 Cells: Potential Role in Antiretroviral Drug Oral Bioavailability and Drug-Drug Interactions

(2010) O. Kis et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Effect of Variations in the Amounts of P-Glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the Human Small Intestine on PBPK Models for Predicting Intestinal First Pass

(2010) Arnaud Bruyère et al.   MOLECULAR PHARMACEUTICS

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1

(2010) P. Annaert et al.   XENOBIOTICA

P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir

(2009) Omar Janneh et al.   ANTIVIRAL THERAPY

Analysis of CYP3A4-HIV-1 protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS

(2009) Mannu Jayakanthan et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

The complexities of antiretroviral drug–drug interactions: role of ABC and SLC transporters

(2009) Olena Kis et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Comparison of ABC Transporter Modulation by Atazanavir in Lymphocytes and Human Brain Endothelial Cells: ABC Transporters Are Involved in the Atazanavir-Limited Passage across an in Vitro Human Model of the Blood–Brain Barrier

(2008) Laurence Bousquet et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats

(2008) C. MacLean et al.   DRUG METABOLISM AND DISPOSITION

Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

(2008) Rose Hayeshi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

(2008) Jason A. Zastre et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Targeted Disruption of Peptide TransporterPept1Gene in Mice Significantly Reduces Dipeptide Absorption in Intestine

(2008) Yongun Hu et al.   MOLECULAR PHARMACEUTICS

Segmental Dependent Transport of Low Permeability Compounds along the Small Intestine Due to P-Glycoprotein: The Role of Efflux Transport in the Oral Absorption of BCS Class III Drugs

(2008) Arik Dahan et al.   MOLECULAR PHARMACEUTICS

Pharmacogenetics of Intestinal Absorption

(2008) Tsutomu Nakamura et al.   Current Drug Delivery

Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors

(2007) Johanna Weiss et al.   EUROPEAN JOURNAL OF PHARMACOLOGY