Predicting Nonlinear Pharmacokinetics of Omeprazole Enantiomers and Racemic Drug Using Physiologically Based Pharmacokinetic Modeling and Simulation: Application to Predict Drug/Genetic Interactions

Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat

(2013) Carl-Christer Johansson et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

PBPK as a tool in regulatory review

(2012) Shiew-Mei Huang   BIOPHARMACEUTICS & DRUG DISPOSITION

Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice

(2012) Joseph A. Grillo et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Stereoselective Interaction Between Tetrahydropalmatine Enantiomers and CYP Enzymes in Human Liver Microsomes

(2012) Si-Yuan Sun et al.   CHIRALITY

The Role of Physiologically Based Pharmacokinetic Modeling in Regulatory Review

(2012) S-M Huang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Predicting Drug Interaction Potential With a Physiologically Based Pharmacokinetic Model: A Case Study of Telithromycin, a Time-Dependent CYP3A Inhibitor

(2012) Md L T Vieira et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Regulatory Experience With Physiologically Based Pharmacokinetic Modeling for Pediatric Drug Trials

(2012) R Leong et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

(2012) Ping Zhao et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers

(2011) Goran Šinko et al.   BIOCHIMIE

The Proton Pump Inhibitor, Omeprazole, but Not Lansoprazole or Pantoprazole, Is a Metabolism-Dependent Inhibitor of CYP2C19: Implications for Coadministration with Clopidogrel

(2011) B. W. Ogilvie et al.   DRUG METABOLISM AND DISPOSITION

Stereoselective Disposition of Proton??Pump Inhibitors

(2008) Tommy Andersson et al.   CLINICAL DRUG INVESTIGATION

Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions

(2008) Jiansong Yang et al.   CURRENT DRUG METABOLISM

Differential Pharmacokinetics and Pharmacodynamics of Methylphenidate Enantiomers

(2008) John S. Markowitz et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY