Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

The Potential for Drug Supersaturation during Intestinal Processing of Lipid-Based Formulations May Be Enhanced for Basic Drugs

(2013) Yan Yan Yeap et al.   MOLECULAR PHARMACEUTICS

Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases via Induction of Supersaturation

(2013) Yan Yan Yeap et al.   MOLECULAR PHARMACEUTICS

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

(2013) Hywel D. Williams et al.   PHARMACEUTICAL RESEARCH

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the In Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations

(2013) Hywel D. Williams et al.   PHARMACEUTICAL RESEARCH

Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

(2012) Jan Bevernage et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

(2012) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid Digestion as a Trigger for Supersaturation: Evaluation of the Impact of Supersaturation Stabilization on the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems

(2012) Mette U. Anby et al.   MOLECULAR PHARMACEUTICS

Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

(2012) Hywel D. Williams et al.   MOLECULAR PHARMACEUTICS

The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation

(2011) Jonathan M. Miller et al.   MOLECULAR PHARMACEUTICS

Design of Lipid-Based Formulations for Oral Administration of Poorly Water-Soluble Drugs: Precipitation of Drug after Dispersion of Formulations in Aqueous Solution

(2009) Kazi Mohsin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone

(2009) Arik Dahan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effect of polymer admixtures on the growth habit of ionic crystals. Study on crystal growth kinetics of potassium dihydrogen phosphate in water/polyol mixtures

(2008) Stephan Machefer et al.   JOURNAL OF CRYSTAL GROWTH

Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs

(2007) Jean F. Cuiné et al.   JOURNAL OF PHARMACEUTICAL SCIENCES