Polydatin: A review of pharmacology and pharmacokinetics

Polydatin Protects against Lipopolysaccharide-Induced Fulminant Hepatic Failure in D-Galactosamine-Sensitized Mice

(2017) M.J. Wu et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock

(2012) Xingmin Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expressionin vitroandin vivovia reduced production of reactive oxygen species

(2012) Y.-D. He et al.   BRITISH JOURNAL OF DERMATOLOGY

Polydatin – a new mitochondria protector for acute severe hemorrhagic shock treatment

(2012) Xingmin Wang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice

(2012) Lvyi Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Polydatin, A Natural Precursor of Resveratrol, Induces β-Defensin Production and Reduces Inflammatory Response

(2012) Giampietro Ravagnan et al.   INFLAMMATION

Polydatin Attenuates Hypoxic Pulmonary Hypertension and Reverses Remodeling through Protein Kinase C Mechanisms

(2012) Qing Miao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polydatin modulates Ca2+ handling, excitation–contraction coupling and β-adrenergic signaling in rat ventricular myocytes

(2012) Jianxin Deng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells

(2012) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice

(2012) Yun-Wei Shi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Polydatin protects learning and memory impairments in a rat model of vascular dementia

(2012) Run-Ping Li et al.   PHYTOMEDICINE

Protective Effects of Polydatin from Polygonum cuspidatum against Carbon Tetrachloride-Induced Liver Injury in Mice

(2012) Hong Zhang et al.   PLoS One

Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization

(2012) Meichun Yuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Plant Polyphenols Regulate Chemokine Expression and Tissue Repair in Human Keratinocytes Through Interaction with Cytoplasmic and Nuclear Components of Epidermal Growth Factor Receptor System

(2011) Saveria Pastore et al.   ANTIOXIDANTS & REDOX SIGNALING

Polydatin up-regulates clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro

(2011) Shu Shiyu et al.   BMC CELL BIOLOGY

Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood–brain barrier permeability for its neuroprotective effect in pMCAO rat brain

(2011) Hui Ji et al.   BRAIN RESEARCH BULLETIN

Anti-inflammatory Effect of Resveratrol and Polydatin by In Vitro IL-17 Modulation

(2011) Giulia Lanzilli et al.   INFLAMMATION

Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells

(2011) Huanhai Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pharmacokinetics and tissue distribution of 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside from traditional Chinese medicine Polygonum multiflorum following oral administration to rats

(2011) Guiyuan Lv et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cardioprotective effect of polydatin against ischemia/reperfusion injury: Roles of protein kinase C and mito KATP activation

(2011) Qing Miao et al.   PHYTOMEDICINE

Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFκB and AhR and EGFR–ERK pathway

(2011) Alla I. Potapovich et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition of melanogenesis by piceid isolated from Polygonum cuspidatum

(2010) Eui Taek Jeong et al.   ARCHIVES OF PHARMACAL RESEARCH

Quantitative structure–antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4′-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: Trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4′-O-β-D-glucopyranoside

(2010) Damian Mikulski et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models

(2010) Jian Ping Gao et al.   FITOTERAPIA

Antioxidant Activity of Resveratrol in Several Fish Lipid Matrices: Effect of Acylation and Glucosylation

(2010) Isabel Medina et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry

(2010) Donggeng Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Bioactivity-guided separation of anti-acidogenic substances againstStreptococcus mutansUA 159 fromPolygonum cuspidatum

(2010) Y-R Kwon et al.   ORAL DISEASES

Polydatin Ameliorates DSS-Induced Colitis in Mice through Inhibition of Nuclear Factor-kappaB Activation

(2010) Jun Yao et al.   PLANTA MEDICA

Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene

(2010) Huihui Li et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

New stilbene dimers against amyloid fibril formation

(2009) Céline Rivière et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

G-quadruplex nucleic acids as therapeutic targets

(2009) Shankar Balasubramanian et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci

(2009) Suk-Ho Ban et al.   FITOTERAPIA

Dose-Dependent Absorption and Metabolism oftrans-Polydatin in rats

(2009) Siyuan Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hypotensive Resuscitation Combined with Polydatin Improve Microcirculation and Survival in a Rabbit Model of Uncontrolled Hemorrhagic Shock in Pregnancy

(2009) Chao Sheng et al.   JOURNAL OF SURGICAL RESEARCH

Modulation of synaptic GABAAreceptor function by zolpidem in substantia nigra pars reticulata

(2008) Li-li ZHANG et al.   ACTA PHARMACOLOGICA SINICA

Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits

(2008) Wei-Wei Xing et al.   BIOMEDICINE & PHARMACOTHERAPY

Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes

(2008) Sabrina Fabris et al.   BIOPHYSICAL CHEMISTRY

Direct Determination of Polydatin and Its Metabolite in Rat Excrement Samples by High-Performance Liquid Chromatography

(2008) Wenting Zhang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

The Polyphenol Piceid Destabilizes Preformed Amyloid Fibrils and Oligomers In Vitro: Hypothesis on Possible Molecular Mechanisms

(2008) Céline Rivière et al.   NEUROCHEMICAL RESEARCH

Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters

(2008) Jian Du et al.   PHYTOMEDICINE

Metabolic profiling reveals therapeutic effects of Herba Cistanches in an animal model of hydrocortisone-induced 'kidney-deficiency syndrome'

(2008) Yunping Qiu et al.   Chinese Medicine