The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction

Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network

(2013) Suleyman Gulsuner et al.   CELL

Amphetamine Paradoxically Augments Exocytotic Dopamine Release and Phasic Dopamine Signals

(2013) D. P. Daberkow et al.   JOURNAL OF NEUROSCIENCE

SLC6 transporters: Structure, function, regulation, disease association and therapeutics

(2013) Akula Bala Pramod et al.   MOLECULAR ASPECTS OF MEDICINE

Amphetamine-induced behavior requires CaMKII-dependent dopamine transporter phosphorylation

(2013) A B Pizzo et al.   MOLECULAR PSYCHIATRY

Common and rare alleles of the serotonin transporter gene,SLC6A4, associated with Tourette's disorder

(2013) Pablo R. Moya et al.   MOVEMENT DISORDERS

Structural basis for action by diverse antidepressants on biogenic amine transporters

(2013) Hui Wang et al.   NATURE

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome

(2013) Nicholas G Campbell et al.   Molecular Autism

Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1

(2012) Stephen J. Fairweather et al.   BIOCHEMICAL JOURNAL

The solute carrier 6 family of transporters

(2012) Stefan Bröer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cyclic GMP-dependent Stimulation of Serotonin Transport Does Not Involve Direct Transporter Phosphorylation by cGMP-dependent Protein Kinase

(2012) Albert Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Dopamine Transporter Serine 7 Modulates Cocaine Analog Binding

(2012) Amy E. Moritz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine Transporter Phosphorylation Site Threonine 53 Regulates Substrate Reuptake and Amphetamine-stimulated Efflux

(2012) James D. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of essential amino acid transport from studies of insect nutrient amino acid transporters of the SLC6 family (NAT-SLC6)

(2012) Dmitri Y. Boudko   JOURNAL OF INSECT PHYSIOLOGY

The Amino Acid-Polyamine-Organocation Superfamily

(2012) Foon H. Wong et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Single Molecule Analysis of Serotonin Transporter Regulation Using Antagonist-Conjugated Quantum Dots Reveals Restricted, p38 MAPK-Dependent Mobilization Underlying Uptake Activation

(2012) J. C. Chang et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association study of Tourette's syndrome

(2012) J M Scharf et al.   MOLECULAR PSYCHIATRY

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP

(2012) Camilo Perez et al.   NATURE

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

(2012) J. Veenstra-VanderWeele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unusual Regulation of a STAT Protein by an SLC6 Family Transporter in C. elegans Epidermal Innate Immunity

(2011) Katja Dierking et al.   Cell Host & Microbe

Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels

(2011) Katie Ann Jennings et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C

(2011) Sonja Sucic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Colocalization and Regulated Physical Association of Presynaptic Serotonin Transporters with A3 Adenosine Receptors

(2011) C.-B. Zhu et al.   MOLECULAR PHARMACOLOGY

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

(2011) M Laura Cremona et al.   NATURE NEUROSCIENCE

Selective p38α MAPK Deletion in Serotonergic Neurons Produces Stress Resilience in Models of Depression and Addiction

(2011) Michael R. Bruchas et al.   NEURON

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Vesicular and Plasma Membrane Transporters for Neurotransmitters

(2011) R. D. Blakely et al.   Cold Spring Harbor Perspectives in Biology

Involvement of threonine 258 and serine 259 motif in amphetamine-induced norepinephrine transporter endocytosis

(2010) Balasubramaniam Annamalai et al.   JOURNAL OF NEUROCHEMISTRY

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

(2010) Derek P Claxton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

(2010) Chong-Bin Zhu et al.   NEUROPSYCHOPHARMACOLOGY

Regulation of monoamine transporters: Role of transporter phosphorylation

(2010) Sammanda Ramamoorthy et al.   PHARMACOLOGY & THERAPEUTICS

l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth

(2009) Koji Oda et al.   CANCER SCIENCE

Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT3

(2009) Dustin Singer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

(2009) R Tabarés-Seisdedos et al.   MOLECULAR PSYCHIATRY

Molecular basis of transport and regulation in the Na+/betaine symporter BetP

(2009) Susanne Ressl et al.   NATURE

Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures

(2009) Zheng Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

(2009) Lucy R. Forrest et al.   PHYSIOLOGY

Disruption of the dopamine transporter-dopamine D2 receptor interaction in schizophrenia

(2009) Frank J.S. Lee et al.   SYNAPSE

Regulatory Properties and Interaction of the C- and N-Terminal Domains of BetP, an Osmoregulated Betaine Transporter fromCorynebacterium glutamicum†

(2008) Vera Ott et al.   BIOCHEMISTRY

Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations

(2008) Simone M.R. Camargo et al.   GASTROENTEROLOGY

Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol

(2008) James D. Foster et al.   JOURNAL OF NEUROCHEMISTRY

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

Targeting the murine serotonin transporter: insights into human neurobiology

(2008) Dennis L. Murphy et al.   NATURE REVIEWS NEUROSCIENCE

Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond

(2008) Vadivel Ganapathy et al.   PHARMACOLOGY & THERAPEUTICS

Mechanism for alternating access in neurotransmitter transporters

(2008) L. R. Forrest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

(2008) S. Weyand et al.   SCIENCE

Going with the Flow: Trafficking-Dependent and -Independent Regulation of Serotonin Transport

(2008) Jennifer A. Steiner et al.   TRAFFIC