Effects of early-life environment and epigenetics on cardiovascular disease risk in children: highlighting the role of twin studies

Metabolic syndrome in children born small-for-gestational age

(2012) María Isabel Hernández et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

(2012) Michael Volkmar et al.   EMBO JOURNAL

450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy

(2012) Bonnie R. Joubert et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

(2012) L. Gordon et al.   GENOME RESEARCH

Is epidemiology ready for epigenetics?

(2012) Caroline L Relton et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease

(2012) Caroline L Relton et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Dietary protein restriction and excess of pregnant German Landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring

(2012) Simone Altmann et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Investigations on Transgenerational Epigenetic Response Down the Male Line in F2 Pigs

(2012) Martin Braunschweig et al.   PLoS One

DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood

(2012) Caroline L. Relton et al.   PLoS One

Prenatal Smoke Exposure and Genomic DNA Methylation in a Multiethnic Birth Cohort

(2011) J. D. Flom et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Epigenetics in cardiovascular disease

(2011) Apurva V Shirodkar et al.   CURRENT OPINION IN CARDIOLOGY

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Expression discordance of monozygotic twins at birth: Effect of intrauterine environment and a possible mechanism for fetal programming

(2011) Lavinia Gordon et al.   Epigenetics

Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans

(2011) Anthony A. Fryer et al.   Epigenetics

Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells

(2011) L. Pirola et al.   GENOME RESEARCH

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

(2011) Emma L. Dempster et al.   HUMAN MOLECULAR GENETICS

Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction

(2011) Rudolf P Talens et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Endothelial vasodilatation in newborns is related to body size and maternal hypertension

(2011) Robbert N.H. Touwslager et al.   JOURNAL OF HYPERTENSION

The Use of Surrogate Vascular Markers in Youth at Risk for Premature Cardiovascular Disease

(2011) C.J. McNeal et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Epigenome-wide association studies for common human diseases

(2011) Vardhman K. Rakyan et al.   NATURE REVIEWS GENETICS

Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis

(2011) Vardhman K. Rakyan et al.   PLoS Genetics

Allelic Skewing of DNA Methylation Is Widespread across the Genome

(2010) Leonard C. Schalkwyk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

(2010) Christopher G Bell et al.   BMC Medical Genomics

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Inflammation in Atherosclerosis:

(2010) Peter Libby et al.   CIRCULATION JOURNAL

DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome

(2010) Miina Ollikainen et al.   HUMAN MOLECULAR GENETICS

Effect of obesity on retinal vascular structure in pre-adolescent children

(2010) Bamini Gopinath et al.   International Journal of Pediatric Obesity

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Epigenetics and cardiovascular disease

(2010) José M. Ordovás et al.   Nature Reviews Cardiology

Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms

(2010) Stephen Tonna et al.   Nature Reviews Nephrology

Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index

(2010) A. P. Feinberg et al.   Science Translational Medicine

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Arterial Stiffness in the Young: Assessment, Determinants, and Implications

(2010) Yiu-Fai Cheung   Korean Circulation Journal

Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study

(2009) LH Lumey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Synergy Between Adiposity, Insulin Resistance, Metabolic Risk Factors, and Inflammation in Adolescents

(2009) R.-C. Huang et al.   DIABETES CARE

Noninvasive Assessment of Subclinical Atherosclerosis in Children and Adolescents

(2009) Elaine M. Urbina et al.   HYPERTENSION

Effect of Birth Parameters on Retinal Vascular Caliber

(2009) Cong Sun et al.   HYPERTENSION

Pediatric triglycerides predict cardiovascular disease events in the fourth to fifth decade of life

(2009) John A. Morrison et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Maternal Alcohol Intake and Offspring Pulse Wave Velocity

(2009) Ruth Morley et al.   Neonatology

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Retinal Vascular Caliber: Systemic, Environmental, and Genetic Associations

(2009) Cong Sun et al.   SURVEY OF OPHTHALMOLOGY

A conceptual framework for the developmental origins of health and disease

(2009) P. D. Gluckman et al.   Journal of Developmental Origins of Health and Disease

Evidence of Arteriolar Narrowing in Low-Birth-Weight Children

(2008) Paul Mitchell et al.   CIRCULATION

Familial (shared environmental and genetic) factors and the foetal origins of cardiovascular diseases and type 2 diabetes: a review of the literature

(2008) N. Bergvall et al.   JOURNAL OF INTERNAL MEDICINE

Pro-opiomelanocortin (POMC)-derived peptides and the regulation of energy homeostasis

(2008) Anthony P. Coll et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA