Merlin, the NF2 Gene Product

Merlin-Deficient Human Tumors Show Loss of Contact Inhibition and Activation of Wnt/β-Catenin Signaling Linked to the PDGFR/Src and Rac/PAK Pathways

(2015) Lu Zhou et al.   NEOPLASIA

Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria

(2013) Scott R. Plotkin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Frequency of loss of heterozygosity of the NF2 gene in schwannomas from Croatian patients

(2012) Nives Pećina-Šlaus et al.   CROATIAN MEDICAL JOURNAL

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus

(2012) Wei Li et al.   EMBO REPORTS

Merlin, a multi-suppressor from cell membrane to the nucleus

(2012) Lu Zhou et al.   FEBS LETTERS

Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity

(2012) Minja Laulajainen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms

(2011) Steven L. Carroll   ACTA NEUROPATHOLOGICA

The molecular biology and novel treatments of vestibular schwannomas

(2011) Brendan Fong et al.   JOURNAL OF NEUROSURGERY

Emerging therapeutic targets in schwannomas and other merlin-deficient tumors

(2011) Sylwia Ammoun et al.   Nature Reviews Neurology

Merlin, a “Magic” Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival

(2010) Ivan Stamenkovic et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Analysis of cytogenetic aberrations in sporadic vestibular schwannoma by comparative genomic hybridization

(2010) Dimitrios Koutsimpelas et al.   JOURNAL OF NEURO-ONCOLOGY

Global Gene Expression Profiling and Tissue Microarray Reveal Novel Candidate Genes and Down-Regulation of the Tumor Suppressor Gene CAV1 in Sporadic Vestibular Schwannomas

(2010) Mads Aarhus et al.   NEUROSURGERY

NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation

(2010) E E Bosco et al.   ONCOGENE

Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas

(2010) K D Hadfield et al.   ONCOGENE

Akt Phosphorylation of Merlin Enhances Its Binding to Phosphatidylinositols and Inhibits the Tumor-Suppressive Activities of Merlin

(2009) M. Okada et al.   CANCER RESEARCH

Genetic and protein changes of E-cadherin in meningiomas

(2009) Nives Pećina-Šlaus et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Molecular biology of familial and sporadic vestibular schwannomas: implications for novel therapeutics

(2009) Michael E. Sughrue et al.   JOURNAL OF NEUROSURGERY

Merlin Is a Potent Inhibitor of Glioma Growth

(2008) Y.-K. I. Lau et al.   CANCER RESEARCH

Magic but treatable? Tumours due to loss of Merlin

(2007) C. O. Hanemann   BRAIN