Regulatory T cells: first steps of clinical application in solid organ transplantation

Novel GMP-Compatible Protocol Employing an Allogeneic B Cell Bank for Clonal Expansion of Allospecific Natural Regulatory T Cells

(2014) S. Landwehr-Kenzel et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Harnessing Regulatory T Cells for Clinical Use in Transplantation: The End of the Beginning

(2014) S. C. Juvet et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets — Results of one year follow-up

(2014) Natalia Marek-Trzonkowska et al.   CLINICAL IMMUNOLOGY

Innate-Like and Conventional T Cell Populations from Hemodialyzed and Kidney Transplanted Patients Are Equally Compromised

(2014) Marine Baron et al.   PLoS One

Single Cell Tracking of Gadolinium Labeled CD4+ T Cells by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

(2013) Amy J. Managh et al.   ANALYTICAL CHEMISTRY

Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation

(2013) Claudio G. Brunstein et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Comparison of Regulatory T Cells in Hemodialysis Patients and Healthy Controls: Implications for Cell Therapy in Transplantation

(2013) B. Afzali et al.   Clinical Journal of the American Society of Nephrology

Posttransplant monitoring of de novo human leukocyte antigen donor-specific antibodies in kidney transplantation

(2013) Chris Wiebe et al.   Current Opinion in Organ Transplantation

Do Cryopreserved Regulatory T Cells Retain Their Suppressive Potency?

(2013) Emily Mavin et al.   TRANSPLANTATION

Permanent CNI Treatment for Prevention of Renal Allograft Rejection in Sensitized Hosts Can Be Replaced by Regulatory T Cells

(2012) A. Siepert et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulatory T-cell therapy for transplantation

(2012) Qizhi Tang et al.   Current Opinion in Organ Transplantation

Administration of CD4+CD25highCD127- Regulatory T Cells Preserves  -Cell Function in Type 1 Diabetes in Children

(2012) N. Marek-Trzonkowska et al.   DIABETES CARE

Human herpesvirus-6 infections in kidney, liver, lung, and heart transplantation: review

(2012) Irmeli Lautenschlager et al.   TRANSPLANT INTERNATIONAL

Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease

(2011) K. L. Hippen et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Requirements for Prolongation of Allograft Survival with Regulatory T Cell Infusion in Lymphosufficient Hosts

(2011) Todd V. Brennan et al.   JOURNAL OF SURGICAL RESEARCH

Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

(2011) K. L. Hippen et al.   Science Translational Medicine

Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells

(2011) P. Sagoo et al.   Science Translational Medicine

Moving to tolerance: Clinical application of T regulatory cells

(2011) Alicia N. McMurchy et al.   SEMINARS IN IMMUNOLOGY

Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials

(2011) Liset H. M. Pengel et al.   TRANSPLANT INTERNATIONAL

Immune Reconstitution Following Rabbit Antithymocyte Globulin

(2010) S. Gurkan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells

(2010) Ross S. Francis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adoptive transfer of CD4+CD25+ regulatory cells combined with low-dose sirolimus and anti-thymocyte globulin delays acute rejection of renal allografts in Cynomolgus monkeys

(2010) Anlun Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

(2010) Satish N Nadig et al.   NATURE MEDICINE

Dialysis treatment and regulatory T cells

(2010) C. Libetta et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ex Vivo–Expanded Human Regulatory T Cells Prevent the Rejection of Skin Allografts in a Humanized Mouse Model

(2010) Fadi Issa et al.   TRANSPLANTATION

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Immunosuppressive Drugs in Kidney Transplantation

(2009) Roberto Marcén   DRUGS

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Combined therapy of CD4+CD25+ regulatory T cells with low-dose sirolimus, but not calcineurin inhibitors, preserves suppressive function of regulatory T cells and prolongs allograft survival in mice

(2009) Anlun Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Differential kinetics of effector and regulatory T cells in patients on calcineurin inhibitor–based drug regimens

(2009) Daniela Presser et al.   KIDNEY INTERNATIONAL

End-stage renal failure and regulatory activities of CD4+CD25bright+FoxP3+ T-cells

(2009) T. K. Hendrikx et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127pos Depletion, Treg Expansion, and Treg Cryopreservation

(2008) Jorieke H. Peters et al.   PLoS One

Can immune monitoring help to minimize immunosuppression in kidney transplantation?

(2008) Joanna Ashton-Chess et al.   TRANSPLANT INTERNATIONAL