Considering RNAi experimental design in parasitic helminths

RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions

(2011) E. Seinen et al.   Briefings in Functional Genomics

Tissue Specificity ofCaenorhabditis elegansEnhanced RNA Interference Mutants

(2011) Jimmy J. Zhuang et al.   GENETICS

Schistosome I/Lamides – A new family of bioactive helminth neuropeptides

(2011) Paul McVeigh et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A genome-scale shRNA resource for transgenic RNAi in Drosophila

(2011) Jian-Quan Ni et al.   NATURE METHODS

siRNA-Like Double-Stranded RNAs Are Specifically Protected Against Degradation in Human Cell Extract

(2011) John A. H. Hoerter et al.   PLoS One

SID-1 is a dsRNA-selective dsRNA-gated channel

(2011) J. D. Shih et al.   RNA

Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni

(2011) Kathrin K. Geyer et al.   Nature Communications

RNAi Effector Diversity in Nematodes

(2011) Johnathan J. Dalzell et al.   PLoS Neglected Tropical Diseases

Polyethyleneimine (PEI) Mediated siRNA Gene Silencing in the Schistosoma mansoni Snail Host, Biomphalaria glabrata

(2011) Matty Knight et al.   PLoS Neglected Tropical Diseases

Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus

(2011) Taisei Kikuchi et al.   PLoS Pathogens

The modification of siRNA with 3′ cholesterol to increase nuclease protection and suppression of native mRNA by select siRNA polyplexes

(2010) Vishakha V. Ambardekar et al.   BIOMATERIALS

Prediction of microRNAs affecting mRNA expression during retinal development

(2010) Amit Arora et al.   BMC DEVELOPMENTAL BIOLOGY

RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA?

(2010) Sandesh Subramanya et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Identification of an RNA-dependent RNA polymerase in Drosophila establishes a common theme in RNA silencing

(2010) Concetta Lipardi et al.   FLY

Redefining regulation of DNA methylation by RNA interference

(2010) Viswanathan Muthusamy et al.   GENOMICS

Short interfering RNA-mediated knockdown of drosha and pasha in undifferentiated Meloidogyne incognita eggs leads to irregular growth and embryonic lethality

(2010) Johnathan J. Dalzell et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Activation of Nippostrongylus brasiliensis infective larvae is regulated by a pathway distinct from the hookworm Ancylostoma caninum

(2010) Stanley Ching-Cheng Huang et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Peroxiredoxins from the plant parasitic root-knot nematode, Meloidogyne incognita, are required for successful development within the host

(2010) Géraldine Dubreuil et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Factors affecting susceptibility to RNA interference in Haemonchus contortus and in vivo silencing of an H11 aminopeptidase gene

(2010) Buddhini Samarasinghe et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A specific antibody to neuropeptide AF1 (KNEFIRFamide) recognizes a small subset of neurons in Ascaris suum: differences from Caenorhabditis elegans

(2010) Paisarn Sithigorngul et al.   JOURNAL OF COMPARATIVE NEUROLOGY

RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design

(2010) Olle Terenius et al.   JOURNAL OF INSECT PHYSIOLOGY

A PAL for Schistosoma mansoni PHM

(2010) Louise E. Atkinson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Distinct Phases of siRNA Synthesis in an Endogenous RNAi Pathway in C. elegans Soma

(2010) Jonathan I. Gent et al.   MOLECULAR CELL

Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs

(2010) Calvin H. Jan et al.   NATURE

Enhanced neuronal RNAi in C. elegans using SID-1

(2010) Andrea Calixto et al.   NATURE METHODS

Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans

(2010) Dimitrios G Zisoulis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

Gene silencing in Echinococcus multilocularis protoscoleces using RNA interference

(2010) Chiaki Mizukami et al.   PARASITOLOGY INTERNATIONAL

Effective delivery of a nematode-repellent peptide using a root-cap-specific promoter

(2010) Catherine J. Lilley et al.   PLANT BIOTECHNOLOGY JOURNAL

RNAi Experiments in D. melanogaster: Solutions to the Overlooked Problem of Off-Targets Shared by Independent dsRNAs

(2010) Erwin Seinen et al.   PLoS One

RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

(2010) Saša Štefanić et al.   PLoS Neglected Tropical Diseases

Development of an In Vivo RNAi Protocol to Investigate Gene Function in the Filarial Nematode, Brugia malayi

(2010) Chuanzhe Song et al.   PLoS Pathogens

Suppressing Glucose Transporter Gene Expression in Schistosomes Impairs Parasite Feeding and Decreases Survival in the Mammalian Host

(2010) Greice Krautz-Peterson et al.   PLoS Pathogens

RNAi and Functional Genomics in Plant Parasitic Nematodes

(2009) M. N. Rosso et al.   Annual Review of Phytopathology

Non-nematode-derived double-stranded RNAs induce profound phenotypic changes in Meloidogyne incognita and Globodera pallida infective juveniles

(2009) Johnathan J. Dalzell et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Short interfering RNA-mediated gene silencing in Globodera pallida and Meloidogyne incognita infective stage juveniles

(2009) Johnathan J. Dalzell et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

RNA interference in a cestode reveals specific silencing of selected highly expressed gene transcripts

(2009) Lisa Pierson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

In situ hybridization of neuropeptide-encoding transcriptsafp-1, afp-3,andafp-4in neurons of the nematodeascaris suum

(2009) Jennifer Cho Nanda et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: A review

(2009) Hanneke Huvenne et al.   JOURNAL OF INSECT PHYSIOLOGY

On the road to reading the RNA-interference code

(2009) Haruhiko Siomi et al.   NATURE

Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs

(2009) Shuo Gu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA interference in schistosomes: machinery and methodology

(2009) GREICE KRAUTZ-PETERSON et al.   PARASITOLOGY

A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni

(2009) Conor R. Caffrey et al.   PLoS One

The SID-1 double-stranded RNA transporter is not selective for dsRNA length

(2009) J. D. Shih et al.   RNA

Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway

(2009) M. Ghildiyal et al.   RNA

Phenotypic Screen of Early-Developing Larvae of the Blood Fluke, Schistosoma mansoni, using RNA Interference

(2009) Marina de Moraes Mourão et al.   PLoS Neglected Tropical Diseases

Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study

(2008) Joseph A. Gredell et al.   BIOTECHNOLOGY AND BIOENGINEERING

C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth

(2008) Johanna Pispa et al.   BMC DEVELOPMENTAL BIOLOGY

Schistosoma japonicum: Inhibition of Mago nashi gene expression by shRNA-mediated RNA interference

(2008) Zhi-rong Zhao et al.   EXPERIMENTAL PARASITOLOGY

Characterisation by RNAi of pioneer genes expressed in the dorsal pharyngeal gland cell of Heterodera glycines and the effects of combinatorial RNAi

(2008) M. Bakhetia et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Attempts to establish RNA interference in the parasitic nematode Heligmosomoides polygyrus

(2008) Matthias Lendner et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

RNA major groove modifications improve siRNA stability and biological activity

(2008) Montserrat Terrazas et al.   NUCLEIC ACIDS RESEARCH

Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium

(2008) Yoshinori Tomoyasu et al.   GENOME BIOLOGY

Schistosoma mansoni: The dicer gene and its expression

(2007) Greice Krautz-Peterson et al.   EXPERIMENTAL PARASITOLOGY

Schistosoma mansoni: Evaluation of an RNAi-based treatment targeting HGPRTase gene

(2007) T.C. Pereira et al.   EXPERIMENTAL PARASITOLOGY

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration

(2007) L MCGONIGLE et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Two hypotheses to explain why RNA interference does not work in animal parasitic nematodes

(2007) M.E. Viney et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade

(2007) Maria E. Morales et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY