Forty Years of Clathrin-coated Vesicles

A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development

(2015) Michael S. Nahorski et al.   BRAIN

CALM Regulates Clathrin-Coated Vesicle Size and Maturation by Directly Sensing and Driving Membrane Curvature

(2015) Sharon E. Miller et al.   DEVELOPMENTAL CELL

Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking

(2015) Ling Yi et al.   HUMAN MOLECULAR GENETICS

Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease

(2015) Jennifer Hirst et al.   HUMAN MOLECULAR GENETICS

ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis

(2015) P. T. Manna et al.   JOURNAL OF CELL SCIENCE

Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking

(2015) Jennifer Hirst et al.   MOLECULAR BIOLOGY OF THE CELL

Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1

(2015) Shweta Jain et al.   MOLECULAR BIOLOGY OF THE CELL

Complex archaea that bridge the gap between prokaryotes and eukaryotes

(2015) Anja Spang et al.   NATURE

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Endocytic sites mature by continuous bending and remodeling of the clathrin coat

(2015) O. Avinoam et al.   SCIENCE

Effect of Clathrin Light Chains on the Stiffness of Clathrin Lattices and Membrane Budding

(2015) Philip N. Dannhauser et al.   TRAFFIC

Intrinsically disordered proteins drive membrane curvature

(2015) David J. Busch et al.   Nature Communications

A balance between membrane elasticity and polymerization energy sets the shape of spherical clathrin coats

(2015) Mohammed Saleem et al.   Nature Communications

AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking

(2014) Niovi Setta-Kaffetzi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The TPLATE Adaptor Complex Drives Clathrin-Mediated Endocytosis in Plants

(2014) Astrid Gadeyne et al.   CELL

Adaptor proteins involved in polarized sorting

(2014) Juan S. Bonifacino   JOURNAL OF CELL BIOLOGY

 1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue

(2014) J. Baltes et al.   JOURNAL OF CELL SCIENCE

Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein–protein interactions

(2014) Georg H. H. Borner et al.   MOLECULAR BIOLOGY OF THE CELL

Clathrin regenerates synaptic vesicles from endosomes

(2014) Shigeki Watanabe et al.   NATURE

Clathrin/AP-2 Mediate Synaptic Vesicle Reformation from Endosome-like Vacuoles but Are Not Essential for Membrane Retrieval at Central Synapses

(2014) Natalia L. Kononenko et al.   NEURON

AP2 controls clathrin polymerization with a membrane-activated switch

(2014) B. T. Kelly et al.   SCIENCE

Unconventional Functions for Clathrin, ESCRTs, and Other Endocytic Regulators in the Cytoskeleton, Cell Cycle, Nucleus, and Beyond: Links to Human Disease

(2014) F. M. Brodsky et al.   Cold Spring Harbor Perspectives in Biology

The Cell Biology of the Endocytic System from an Evolutionary Perspective

(2014) J. G. Wideman et al.   Cold Spring Harbor Perspectives in Biology

Clathrin-Independent Pathways of Endocytosis

(2014) S. Mayor et al.   Cold Spring Harbor Perspectives in Biology

Characterization of TSET, an ancient and widespread membrane trafficking complex

(2014) Jennifer Hirst et al.   eLife

A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing

(2014) Perunthottathu K Umasankar et al.   eLife

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

(2014) Yumei Wu et al.   eLife

The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex

(2014) Gunther Hollopeter et al.   eLife

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

(2014) Xiaofei Jia et al.   eLife

MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy

(2013) Diego Martinelli et al.   BRAIN

Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1

(2013) Xuefeng Ren et al.   CELL

The Adaptor Protein-1 μ1B Subunit Expands the Repertoire of Basolateral Sorting Signal Recognition in Epithelial Cells

(2013) Xiaoli Guo et al.   DEVELOPMENTAL CELL

A Nobel Prize for membrane traffic: Vesicles find their journey’s end

(2013) Ira Mellman et al.   JOURNAL OF CELL BIOLOGY

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

(2013) York Posor et al.   NATURE

A cost–benefit analysis of the physical mechanisms of membrane curvature

(2013) Jeanne C. Stachowiak et al.   NATURE CELL BIOLOGY

Regulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membrane

(2013) J. R. Mayers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis

(2013) Pei Zhi Cheryl Chia et al.   TRAFFIC

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

The First Five Seconds in the Life of a Clathrin-Coated Pit

(2012) Emanuele Cocucci et al.   CELL

Endocytosis of G Protein-Coupled Receptors Is Regulated by Clathrin Light Chain Phosphorylation

(2012) Filipe Ferreira et al.   CURRENT BIOLOGY

Distinct and Overlapping Roles for AP-1 and GGAs Revealed by the “Knocksideways” System

(2012) Jennifer Hirst et al.   CURRENT BIOLOGY

The Clathrin Adaptor AP-1A Mediates Basolateral Polarity

(2012) Diego Gravotta et al.   DEVELOPMENTAL CELL

Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles

(2012) Georg H.H. Borner et al.   JOURNAL OF CELL BIOLOGY

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

(2012) Jeremy H. Herskowitz et al.   MOLECULAR BIOLOGY OF THE CELL

A human genome-wide screen for regulators of clathrin-coated vesicle formation reveals an unexpected role for the V-ATPase

(2012) Patrycja Kozik et al.   NATURE CELL BIOLOGY

Bending membranes

(2012) Tom Kirchhausen   NATURE CELL BIOLOGY

Reconstitution of clathrin-coated bud and vesicle formation with minimal components

(2012) Philip N. Dannhauser et al.   NATURE CELL BIOLOGY

Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning

(2012) P. K. Umasankar et al.   NATURE CELL BIOLOGY

Membrane bending by protein–protein crowding

(2012) Jeanne C. Stachowiak et al.   NATURE CELL BIOLOGY

Signal-Mediated, AP-1/Clathrin-Dependent Sorting of Transmembrane Receptors to the Somatodendritic Domain of Hippocampal Neurons

(2012) Ginny G. Farías et al.   NEURON

The Unique GGA Clathrin Adaptor of Drosophila melanogaster Is Not Essential

(2012) Shan Luan et al.   PLoS One

Adaptor Protein Complexes AP-4 and AP-5: New Players in Endosomal Trafficking and Progressive Spastic Paraplegia

(2012) Jennifer Hirst et al.   TRAFFIC

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers

(2012) Comert Kural et al.   Cell Reports

A Feedback Loop between Dynamin and Actin Recruitment during Clathrin-Mediated Endocytosis

(2012) Marcus J. Taylor et al.   PLOS BIOLOGY

The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM

(2011) Sharon E. Miller et al.   CELL

Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.

(2011) Camille Lobry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endophilin Drives the Fast Mode of Vesicle Retrieval in a Ribbon Synapse

(2011) A. Llobet et al.   JOURNAL OF NEUROSCIENCE

Clathrin Mediates Endocytosis and Polar Distribution of PIN Auxin Transporters inArabidopsis

(2011) Saeko Kitakura et al.   PLANT CELL

The Generation of Curved Clathrin Coats from Flat Plaques

(2011) Wouter K. den Otter et al.   TRAFFIC

The Fifth Adaptor Protein Complex

(2011) Jennifer Hirst et al.   PLOS BIOLOGY

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

Clathrin-dependent APP endocytosis and Aβ secretion are highly sensitive to the level of plasma membrane cholesterol

(2010) Jack-Christophe Cossec et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Large-Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the AP2 Clathrin Adaptor Complex

(2010) Lauren P. Jackson et al.   CELL

Conformation Switching of Clathrin Light Chain Regulates Clathrin Lattice Assembly

(2010) Jeremy D. Wilbur et al.   DEVELOPMENTAL CELL

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

Rapid Inactivation of Proteins by Rapamycin-Induced Rerouting to Mitochondria

(2010) Margaret S. Robinson et al.   DEVELOPMENTAL CELL

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

Systems survey of endocytosis by multiparametric image analysis

(2010) Claudio Collinet et al.   NATURE

Adaptin-like protein TPLATE and clathrin recruitment during plant somatic cytokinesis occurs via two distinct pathways

(2010) D. Van Damme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FCHo Proteins Are Nucleators of Clathrin-Mediated Endocytosis

(2010) W. M. Henne et al.   SCIENCE

Structure of the PTEN-like Region of Auxilin, a Detector of Clathrin-Coated Vesicle Budding

(2010) Rong Guan et al.   STRUCTURE

A Screen for Endocytic Motifs

(2010) Patrycja Kozik et al.   TRAFFIC

Electron Tomography of RabA4b- and PI-4Kβ1-Labeled Trans Golgi Network Compartments in Arabidopsis

(2010) Byung-Ho Kang et al.   TRAFFIC

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

First and last ancestors: reconstructing evolution of the endomembrane system with ESCRTs, vesicle coat proteins, and nuclear pore complexes

(2009) Mark C Field et al.   CURRENT OPINION IN CELL BIOLOGY

Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation

(2009) Amanda Reider et al.   EMBO JOURNAL

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly

(2009) Yi Xing et al.   EMBO JOURNAL

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Clathrin adaptor AP-1 complex excludes multiple postsynaptic receptors from axons in C. elegans

(2009) M. A. Margeta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism

(2009) S. Vassilopoulos et al.   SCIENCE

Stoned

(2009) A. Marie Phillips et al.   TRAFFIC

Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation

(2009) Dinah Loerke et al.   PLOS BIOLOGY

Cargo-sorting signals promote polymerization of adaptor protein-1 in an Arf-1·GTP-independent manner

(2008) Intaek Lee et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Binding of cargo sorting signals to AP-1 enhances its association with ADP ribosylation factor 1–GTP

(2008) Intaek Lee et al.   JOURNAL OF CELL BIOLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Accumulation of AMPA Receptors in Autophagosomes in Neuronal Axons Lacking Adaptor Protein AP-4

(2008) Shinji Matsuda et al.   NEURON

Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord

(2008) Alexandre Montpetit et al.   PLoS Genetics

AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes

(2007) Maryssa Canuel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS