Attenuation ofβ-Amyloid-Induced Oxidative Cell Death by Sulforaphane via Activation of NF-E2-Related Factor 2

Alzheimer's Disease: Cerebrovascular Dysfunction, Oxidative stress, and Advanced Clinical Therapies

(2017) Michael W. Marlatt et al.   JOURNAL OF ALZHEIMERS DISEASE

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model

(2012) Hyunjin Vincent Kim et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Targeting Heme Oxygenase-1 for Neuroprotection and Neuroinflammation in Neurodegenerative Diseases

(2012) Agnieszka Jazwa et al.   CURRENT DRUG TARGETS

Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications

(2011) Young-Sam Keum   Annals of the New York Academy of Sciences

Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism

(2011) Agnieszka Jazwa et al.   ANTIOXIDANTS & REDOX SIGNALING

Modification of Keap1 Cysteine Residues by Sulforaphane

(2011) Chenqi Hu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Phytochemicals Resveratrol and Sulforaphane as Potential Agents for Enhancing the Anti-Tumor Activities of Conventional Cancer Therapies

(2011) Bettina M. Kaminski et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Sulforaphane inhibits mitochondrial permeability transition and oxidative stress

(2011) Tiffany Greco et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cruciferous Vegetable Phytochemical Sulforaphane Affects Phase II Enzyme Expression and Activity in Rat Cardiomyocytes through Modulation of Akt Signaling Pathway

(2011) Emanuela Leoncini et al.   JOURNAL OF FOOD SCIENCE

Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage

(2011) Gang Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Activation of the Nuclear Factor E2-Related Factor 2/Antioxidant Response Element Pathway Is Neuroprotective after Spinal Cord Injury

(2011) Xiaoliang Wang et al.   JOURNAL OF NEUROTRAUMA

Transcription Factor Nrf2 Protects the Spinal Cord from Inflammation Produced by Spinal Cord Injury

(2011) Lei Mao et al.   JOURNAL OF SURGICAL RESEARCH

Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner

(2011) Hua Jin   Molecular Medicine Reports

The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

(2010) Yuan Hong et al.   ACTA PHARMACOLOGICA SINICA

Potential therapeutic agents against Alzheimer’s disease from natural sources

(2010) So-Young Park   ARCHIVES OF PHARMACAL RESEARCH

Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme

(2010) Zhang Ping et al.   BRAIN RESEARCH

Protective effect of sulforaphane against oxidative stress: Recent advances

(2010) Carlos Enrique Guerrero-Beltrán et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes

(2010) David Vauzour et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nutraceutical Antioxidants as Novel Neuroprotective Agents

(2010) Natalie A. Kelsey et al.   MOLECULES

Natural products as a source of Alzheimer's drug leads

(2010) Philip Williams et al.   NATURAL PRODUCT REPORTS

Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage

(2010) Petra Bergström et al.   NEUROPHARMACOLOGY

Oxidative stress in Alzheimer disease

(2010) Alejandro Gella et al.   Cell Adhesion & Migration

Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention

(2009) Ka Lung Cheung et al.   AAPS Journal

Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

(2009) Rukhsana Sultana et al.   ACTA NEUROPATHOLOGICA

Protection against amyloid beta cytotoxicity by sulforaphane: Role of the proteasome

(2009) Hyun-Min Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures

(2009) Aubrey Siebert et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation

(2009) Lucian Soane et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sulforaphane improves cognitive function administered following traumatic brain injury

(2009) Pramod K. Dash et al.   NEUROSCIENCE LETTERS

Heme Oxygenase-1 as a Therapeutic Target in Neurodegenerative Diseases and Brain Infections

(2008) Antonio Cuadrado et al.   CURRENT PHARMACEUTICAL DESIGN

Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation

(2008) Camelia A. Danilov et al.   GLIA

Regulation of Neuronal Glutathione Synthesis

(2008) Koji Aoyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath

(2008) Ana I. Rojo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Therapeutic Strategies for Alzheimer’s Disease

(2008) Donna M. Barten et al.   MOLECULAR NEUROBIOLOGY

Direct and indirect antioxidant properties of inducers of cytoprotective proteins

(2008) Albena T. Dinkova-Kostova et al.   MOLECULAR NUTRITION & FOOD RESEARCH