Circadian Dysregulation: The Next Frontier in Obstructive Sleep Apnea Research

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study

(2018) David Montaigne et al.   LANCET

Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer Disease

(2018) Erik S. Musiek et al.   JAMA Neurology

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

(2018) Gabriele Sulli et al.   NATURE

A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes

(2017) Minoru Kobayashi et al.   FEBS Journal

CYCLOPS reveals human transcriptional rhythms in health and disease

(2017) Ron C. Anafi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Milieu and Cardiovascular Homeostasis in Children With Obstructive Sleep Apnea

(2017) David F. Smith et al.   SLEEP

Altered Nocturnal Cardiovascular Control in Children With Sleep-Disordered Breathing

(2017) Fatima El-Hamad et al.   SLEEP

Short Sleep Duration, Obstructive Sleep Apnea, Shiftwork, and the Risk of Adverse Cardiovascular Events in Patients After an Acute Coronary Syndrome

(2017) Laura K. Barger et al.   Journal of the American Heart Association

Inflammatory Milieu and Cardiovascular Homeostasis in Children With Obstructive Sleep Apnea

(2017) David F. Smith et al.   SLEEP

Altered Nocturnal Cardiovascular Control in Children With Sleep-Disordered Breathing

(2017) Fatima El-Hamad et al.   SLEEP

Sleep Measures and Morning Plasma TNF-α Levels in Children with Sleep-Disordered Breathing

(2017) David Gozal et al.   SLEEP

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Consequences of Circadian and Sleep Disturbances for the Cardiovascular System

(2015) Faisal J. Alibhai et al.   CANADIAN JOURNAL OF CARDIOLOGY

Delayed brachial artery dilation response and increased resting blood flow velocity in young children with mild sleep-disordered breathing

(2015) Anna Kontos et al.   SLEEP MEDICINE

Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy

(2014) Jonathan C. Jun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased Prevalence of Sleep-Disordered Breathing in Adults

(2013) P. E. Peppard et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Obstructive sleep apnea and cardiovascular risk: Meta-analysis of prospective cohort studies

(2013) Jia-Yi Dong et al.   ATHEROSCLEROSIS

Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea

(2013) Siriporn Chatsuriyawong et al.   BMC Medical Genomics

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Epigenetic Changes in the eNOS Gene

(2013) Leila Kheirandish-Gozal et al.   CHEST

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

(2013) Erik S. Musiek et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

(2012) Tobias Eckle et al.   NATURE MEDICINE

Adverse Metabolic Consequences in Humans of Prolonged Sleep Restriction Combined with Circadian Disruption

(2012) O. M. Buxton et al.   Science Translational Medicine

Baroreflex Sensitivity after Adenotonsillectomy in Children with Obstructive Sleep Apnea during Wakefulness and Sleep

(2012) Joseph A. Crisalli et al.   SLEEP

Endothelial Dysfunction in Children Without Hypertension

(2011) Rakesh Bhattacharjee et al.   CHEST

Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies

(2011) Francesco P. Cappuccio et al.   EUROPEAN HEART JOURNAL

The daily rhythm of mice

(2011) Jürgen A. Ripperger et al.   FEBS LETTERS

Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection

(2011) Xinguo Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA

(2011) Georgia Malakasioti et al.   Sleep and Breathing

Circadian Timing in Cancer Treatments

(2010) Francis Lévi et al.   Annual Review of Pharmacology and Toxicology

Administration–time-dependent effects of blood pressure-lowering medications: basis for the chronotherapy of hypertension

(2010) Michael H. Smolensky et al.   BLOOD PRESSURE MONITORING

INFLUENCE OF CIRCADIAN TIME OF HYPERTENSION TREATMENT ON CARDIOVASCULAR RISK: RESULTS OF THE MAPEC STUDY

(2010) Ramón C. Hermida et al.   CHRONOBIOLOGY INTERNATIONAL

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1α heterozygous-null mice after burn wounding

(2010) Xianjie Zhang et al.   WOUND REPAIR AND REGENERATION

Baroreflex Gain in Children with Obstructive Sleep Apnea

(2009) Keith McConnell et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Short Communication: Ischemia/Reperfusion Tolerance Is Time-of-Day–Dependent

(2009) David J. Durgan et al.   CIRCULATION RESEARCH

Prevalence and Factors Associated With Circadian Blood Pressure Patterns in Hypertensive Patients

(2009) Alejandro de la Sierra et al.   HYPERTENSION

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Adverse metabolic and cardiovascular consequences of circadian misalignment

(2009) F. A. J. L. Scheer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic inflammation in non-obese children with obstructive sleep apnea

(2007) David Gozal et al.   SLEEP MEDICINE