Osteoblastogenesis regulation signals in bone remodeling

Lrp5 functions in bone to regulate bone mass

(2011) Yajun Cui et al.   NATURE MEDICINE

Generation and Selection of Novel Fully Human Monoclonal Antibodies That Neutralize Dickkopf-1 (DKK1) Inhibitory Functionin Vitroand Increase Bone Massin Vivo

(2010) Helmut Glantschnig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of transforming growth factor β on parathyroid hormone receptor binding and cAMP formation in rat osteosarcoma cells

(2010) Patricia K. Seitz et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

(2010) Vijay K Yadav et al.   NATURE MEDICINE

Osteoporosis: impact on health and economics

(2010) Nicholas Harvey et al.   Nature Reviews Rheumatology

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

(2009) Peter V.N. Bodine et al.   BONE

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

(2009) Vijay K. Yadav et al.   CELL

PTH and PTHrP signaling in osteoblasts

(2009) Nabanita S. Datta et al.   CELLULAR SIGNALLING

Bidirectional Signaling through EphrinA2-EphA2 Enhances Osteoclastogenesis and Suppresses Osteoblastogenesis

(2009) Naoko Irie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parathyroid hormone (PTH)–induced bone gain is blunted in SOST overexpressing and deficient mice

(2009) Ina Kramer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1

(2009) W. Xing et al.   MOLECULAR AND CELLULAR BIOLOGY

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone

(2008) David Goltzman   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

EphrinB2 Regulation by PTH and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts

(2008) Elizabeth H Allan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Building bone to reverse osteoporosis and repair fractures

(2008) Sundeep Khosla et al.   JOURNAL OF CLINICAL INVESTIGATION

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

Notch Signaling in Osteoblasts

(2008) E. Canalis   Science Signaling

Parathyroid Hormone Regulates Transforming Growth Factor β1 and β2 Synthesis in Osteoblasts Via Divergent Signaling Pathways

(2006) Yanhong Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH