2,3′,4,4′,5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway

The PI3K/Akt and ERK pathways elevate thyroid hormone receptor β1 and TRH receptor to decrease thyroid hormones after exposure to PCB153 and p,p′-DDE

(2015) Changjiang Liu et al.   CHEMOSPHERE

Molecular mechanisms of human thyrocyte dysfunction induced by low concentrations of polychlorinated biphenyl 118 through the Akt/FoxO3a/NIS pathway

(2015) Hongwei Guo et al.   JOURNAL OF APPLIED TOXICOLOGY

Molecular Mechanisms of 2, 3′, 4, 4′, 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells

(2015) Hui Yang et al.   PLoS One

Rola układu immunologicznego oraz udział cytokin w patomechanizmie autoimmunologicznej choroby tarczycy (AITD)

(2014) Hanna Mikoś et al.   Endokrynologia Polska

Interleukins as markers of inflammation in malignant and benign thyroid disease

(2014) Xeni Provatopoulou et al.   INFLAMMATION RESEARCH

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

(2014) Banrida Wahlang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Morphological and functional deterioration of the rat thyroid following chronic exposure to low-dose PCB118

(2013) Jin-Mei Tang et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Aryl Hydrocarbon Receptor Activation Attenuates Per1 Gene Induction and Influences Circadian Clock Resetting

(2013) Can-Xin Xu et al.   TOXICOLOGICAL SCIENCES

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

(2013) AlberTinka J. Murk et al.   TOXICOLOGY IN VITRO

Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro

(2013) Eiko Koike et al.   TOXICOLOGY IN VITRO

A pro-inflammatory role of deubiquitinating enzyme cylindromatosis (CYLD) in vascular smooth muscle cells

(2012) Shuai Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inflammatory Pathway Genes Belong to Major Targets of Persistent Organic Pollutants in Adipose Cells

(2012) Min Ji Kim et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

JNK pathway decreases thyroid hormones via TRH receptor: A novel mechanism for disturbance of thyroid hormone homeostasis by PCB153

(2012) Changjiang Liu et al.   TOXICOLOGY

An in vivo animal study assessing long-term changes in hypothalamic cytokines following perinatal exposure to a chemical mixture based on Arctic maternal body burden

(2011) Shawn Hayley et al.   Environmental Health

Anaemia, hypothyroidism and immune suppression associated with polychlorinated biphenyl exposure in bottlenose dolphins (Tursiops truncatus)

(2011) L. H. Schwacke et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Thyroid Gland: A Crossroad in Inflammation-Induced Carcinoma? An Ongoing Debate with New Therapeutic Potential.

(2010) A. Bozec et al.   CURRENT MEDICINAL CHEMISTRY

Expression of cytokines in the thyroid: thyrocytes as potential cytokine producers

(2009) G. Aust et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent

(2009) Zuzana Majkova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

(2008) Alvaro Puga et al.   BIOCHEMICAL PHARMACOLOGY

Activation of the cAMP pathway synergistically increases IL-1-induced IL-6 gene expression in FRTL-5 thyroid cells: Involvement of AP-1 transcription factors

(2008) Nicolas Szabo-Fresnais et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes

(2007) Zdenek Dvorak et al.   BIOCHEMICAL PHARMACOLOGY