Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse

Integrating toxicogenomics into human health risk assessment: Lessons learned from the benzo[a]pyrene case study

(2015) Nikolai L. Chepelev et al.   CRITICAL REVIEWS IN TOXICOLOGY

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

(2015) Ivy Moffat et al.   CRITICAL REVIEWS IN TOXICOLOGY

Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells

(2015) Heng-Hong Li et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS

(2015) Tod A. Harper et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Neurotoxicity may be an overlooked consequence of benzo[a]pyrene exposure that is relevant to human health risk assessment

(2015) Nikolai L. Chepelev et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

(2014) Laura E. Wohak et al.   ARCHIVES OF TOXICOLOGY

MBD5 regulates iron metabolism via methylation-independent genomic targeting ofFth1through KAT2A in mice

(2014) Yunlong Tao et al.   BRITISH JOURNAL OF HAEMATOLOGY

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma

(2013) Fangli Ren et al.   CELLULAR SIGNALLING

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis

(2013) M. E. Meek et al.   JOURNAL OF APPLIED TOXICOLOGY

Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene

(2013) Amal I. Malik et al.   MUTAGENESIS

FCHSD1 and FCHSD2 Are Expressed in Hair Cell Stereocilia and Cuticular Plate and Regulate Actin Polymerization In Vitro

(2013) Huiren Cao et al.   PLoS One

Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan

(2013) Anna Francina Jackson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes

(2012) Ji Zhang et al.   Autophagy

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Subchronic Oral Exposure to Benzo(a)pyrene Leads to Distinct Transcriptomic Changes in the Lungs That Are Related to Carcinogenesis

(2012) Sarah Labib et al.   TOXICOLOGICAL SCIENCES

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

(2012) Lisbeth K. Siddens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hepatic mRNA, microRNA, and miR-34a-Target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation

(2011) Amal I. Malik et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and dna adducts in mutaTMmouse

(2011) Christine L. Lemieux et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Regulation of iron pathways in response to hypoxia

(2010) Nikolai L. Chepelev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

(2010) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response

(2010) Ornella Cazzalini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Ontology-Based Meta-Analysis of Global Collections of High-Throughput Public Data

(2010) Ilya Kupershmidt et al.   PLoS One

Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment

(2010) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Low-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cells

(2010) Qian Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

GeneCards Version 3: the human gene integrator

(2010) M. Safran et al.   Database-The Journal of Biological Databases and Curation

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress

(2009) Dipti Mangal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Targeting erythroblast-specific apoptosis in experimental anemia

(2008) Abhinav Diwan et al.   APOPTOSIS