Journal
ORGANIC LETTERS
Volume 11, Issue 16, Pages 3730-3733Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol901347t
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Funding
- Natural Science Foundation of China [20872126]
- Zhejiang Provincial Natural Science Foundation of China [R407106]
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A wide range of silyl enol ethers undergo the reactions with N,N-dimethylanilines in the presence of transition metal catalysts under mild conditions to give beta-arylamino ketones. In the cases of silyl enol ethers derived from unsymmetrical ketones, regiospecific addition of carbonyl compounds was obtained at the olefinic position of silyl enol ether.
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