TsOH·H2O-mediated N-amidation of quinoline N-oxides: facile and regioselective synthesis of N-(quinolin-2-yl)amides

Selectfluor-mediated regioselective nucleophilic functionalization of N-heterocycles under metal- and base-free conditions

(2018) Long-Yong Xie et al.   GREEN CHEMISTRY

Quinoline hybrids and their antiplasmodial and antimalarial activities

(2017) Yuan-Qiang Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A base-free, ultrasound accelerated one-pot synthesis of 2-sulfonylquinolines in water

(2017) Long-Yong Xie et al.   GREEN CHEMISTRY

Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents

(2017) Philippe Panchaud et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

(2017) Anthony V. Pensa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lewis Acid Catalyzed Dehydrogenative Coupling of Tertiary Propargylic Alcohols with Quinoline N-Oxides

(2017) Ya-Ping Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Local epigenetic reprogramming induced by G-quadruplex ligands

(2017) Guillaume Guilbaud et al.   Nature Chemistry

Nitrilium ions – synthesis and applications

(2017) Tom van Dijk et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Strategic Approach to 8-Azacoumarins

(2017) Dong Wang et al.   ORGANIC LETTERS

Iodine-Catalyzed Direct C–H Alkenylation of Azaheterocycle N-Oxides with Alkenes

(2017) Zhenhao Zhang et al.   ORGANIC LETTERS

Fast, Base-Free and Aqueous Synthesis of Quinolin-2(1H)-ones under Ambient Conditions

(2017) Long-Yong Xie et al.   ACS Sustainable Chemistry & Engineering

A direct metal-free C2–H functionalization of quinoline N-oxides: a highly selective amination and alkylation strategy towards 2-substituted quinolines

(2017) Wen-Zhu Bi et al.   Organic Chemistry Frontiers

Transition-Metal-Free Regioselective Alkylation of Pyridine N -Oxides Using 1,1-Diborylalkanes as Alkylating Reagents

(2016) Woohyun Jo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 1H-pyrrolo[3,2-h]quinoline-8-amine derivatives that target CTG trinucleotide repeats

(2016) Jun Matsumoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nonclassical Routes for Amide Bond Formation

(2016) Renata Marcia de Figueiredo et al.   CHEMICAL REVIEWS

In Situ Generated HypoIodite Activator for the C2 Sulfonylation of Heteroaromatic N-oxides

(2016) Yuan Su et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Developments in Amide Synthesis Using Nonactivated Starting Materials

(2016) Andrea Ojeda-Porras et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalyst and solvent-free alkylation of quinoline N-oxides with olefins: A direct access to quinoline-substituted α-hydroxy carboxylic derivatives

(2016) Rakesh Kumar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

C2-Alkenylation of N-heteroaromatic compounds via Brønsted acid catalysis

(2016) Giacomo E. M. Crisenza et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cu-Catalyzed Deoxygenative C2-Sulfonylation Reaction of Quinoline N-Oxides with Sodium Sulfinate

(2016) Bingnan Du et al.   ORGANIC LETTERS

Acid-Free Silver-Catalyzed Cross-Dehydrogenative Carbamoylation of Pyridines with Formamides

(2016) Wei Han et al.   SYNLETT

A review on anticancer potential of bioactive heterocycle quinoline

(2015) Obaid Afzal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

(2015) Maris A. Cinelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxidative cross-coupling of pyridine N-oxides and ethers between C(sp2)–H/C(sp3)–H bonds under transition-metal-free conditions

(2015) Wei Sun et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Metal-free methylation of a pyridine N-oxide C–H bond by using peroxides

(2015) Gang Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper(ii)-catalyzed electrophilic amination of quinoline N-oxides with O-benzoyl hydroxylamines

(2015) Gang Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Gold-catalyzed α-furanylations of quinoline N-oxides with alkenyldiazo carbonyl species

(2015) Vinayak Vishnu Pagar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Benzofuro[3,2-b]pyridines via Palladium-Catalyzed Dual C–H Activation of 3-Phenoxypyridine 1-Oxides

(2015) Wei Sun et al.   ORGANIC LETTERS

Base-Promoted Cross-Dehydrogenative Coupling of Quinoline N-Oxides with 1,3-Azoles

(2015) Xiaopei Chen et al.   ORGANIC LETTERS

Regioselective Metal-Free Cross-Coupling of Quinoline N-Oxides with Boronic Acids

(2015) Luis Bering et al.   ORGANIC LETTERS

The development of carbene-stabilized N–O radical coupling strategy in metal-free regioselective C–H azidation of quinoline N-oxides

(2015) Pan Li et al.   Organic Chemistry Frontiers

Copper-catalyzed direct C–H arylation of pyridine N-oxides with arylboronic esters: one-pot synthesis of 2-arylpyridines

(2014) Yan Shen et al.   CHEMICAL COMMUNICATIONS

Practical preparation of challenging amides from non-nucleophilic amines and esters under flow conditions

(2014) Johannes L. Vrijdag et al.   CHEMICAL COMMUNICATIONS

Direct regioselective phosphonation of heteroaryl N-oxides with H-phosphonates under metal and external oxidant free conditions

(2014) Hui Wang et al.   CHEMICAL COMMUNICATIONS

Conversion of Pyridine N-Oxides to Tetrazolopyridines

(2014) Shanshan Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

2-Aminopyridines via Reaction of Pyridine N-Oxides and Activated Isocyanides

(2014) Mitchell Vamos et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct, Catalytic, and Regioselective Synthesis of 2-Alkyl-, Aryl-, and Alkenyl-Substituted N-Heterocycles from N-Oxides

(2014) Oleg V. Larionov et al.   ORGANIC LETTERS

Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand

(2013) Pierre Murat et al.   CHEMICAL COMMUNICATIONS

Copper-catalysed amidation of 2-chloro-pyridines

(2013) Lionel Nicolas et al.   RSC Advances

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct DehydrativeN-Pyridinylation of Amides

(2009) Jonathan William Medley et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Alkenylation of Quinoline-N-oxides via C−H Activation under External-Oxidant-Free Conditions

(2009) Junliang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

(2008) Raphaël Rodriguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY