Towards novel efficient and stable nuclear import signals: synthesis and properties of trimethylguanosine cap analogs modified within the 5′,5′-triphosphate bridge

Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes

(2014) Joanna Kowalska et al.   NUCLEIC ACIDS RESEARCH

Synthesis and evaluation of stability of m3G-CAP analogues in serum-supplemented medium and cytosolic extract

(2013) Malgorzata Honcharenko et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potential therapeutic applications of RNA cap analogs

(2013) Marcin Ziemniak et al.   Future Medicinal Chemistry

Chemical Synthesis of U1 snRNA Derivatives

(2013) Akihiro Ohkubo et al.   ORGANIC LETTERS

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

(2012) Anna M. Rydzik et al.   BIOORGANIC & MEDICINAL CHEMISTRY

DNA nanostructure serum stability: greater than the sum of its parts

(2012) Justin W. Conway et al.   CHEMICAL COMMUNICATIONS

Capping of oligonucleotides with “clickable” m3G-CAPs

(2012) Malgorzata Honcharenko et al.   RSC Advances

Synthesis of a new class of ribose functionalized dinucleotide cap analogues for biophysical studies on interaction of cap-binding proteins with the 5′ end of mRNA

(2011) Marzena Jankowska-Anyszka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of 5′-Terminal Capped Oligonucleotides Using O–N Phosphoryl Migration of Phosphoramidite Derivatives

(2011) Akihiro Ohkubo et al.   ORGANIC LETTERS

Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH

(2011) W. Su et al.   RNA

hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNA

(2011) Guangwen Lu et al.   Protein & Cell

RNA nucleotide methylation

(2011) Yuri Motorin et al.   Wiley Interdisciplinary Reviews-RNA

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

(2010) A N Kuhn et al.   GENE THERAPY

Antisense oligonucleotides and spinal muscular atrophy: skipping along

(2010) A. H. M. Burghes et al.   GENES & DEVELOPMENT

Synthetic mRNA cap analogs with a modified triphosphate bridge – synthesis, applications and prospects

(2010) Jacek Jemielity et al.   NEW JOURNAL OF CHEMISTRY

Efficient solid-phase synthesis of oligodeoxynucleotides having a 5′-terminal 2,2,7-trimethylguanosine pyrophosphate linkage

(2009) Akihiro Ohkubo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation

(2009) Joanna Kowalska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

eIF4E: New Family Members, New Binding Partners, New Roles

(2009) Robert E. Rhoads   JOURNAL OF BIOLOGICAL CHEMISTRY

A synthetic snRNA m3G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids

(2009) Pedro M. D. Moreno et al.   NUCLEIC ACIDS RESEARCH

Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1

(2009) Thomas Monecke et al.   NUCLEIC ACIDS RESEARCH

The structural basis for cap binding by influenza virus polymerase subunit PB2

(2008) Delphine Guilligay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS

(2008) J. Kowalska et al.   RNA