The effect of the 4-amino functionality on the photophysical and DNA binding properties of alkyl-pyridinium derived 1,8-naphthalimides

Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents

(2013) Swagata Banerjee et al.   CHEMICAL SOCIETY REVIEWS

Fluorescenttren-based 4-amino-1,8-naphthalimide sensor for Cu(II) based on the use of the (fluorophore–spacer–receptor) photoinduced electron transfer (PET) principle

(2013) Emma B. Veale et al.   SUPRAMOLECULAR CHEMISTRY

3-Nitro-naphthalimide and nitrogen mustard conjugate NNM-25 induces hepatocellular carcinoma apoptosis via PARP-1/p53 pathway

(2012) Song-qiang Xie et al.   APOPTOSIS

Photophysical and biological investigation of novel luminescent Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's bases as cellular imaging agents

(2012) Robert B. P. Elmes et al.   CHEMICAL COMMUNICATIONS

Synthesis and photophysical evaluation of a pyridinium 4-amino-1,8-naphthalimide derivative that upon intercalation displays preference for AT-rich double-stranded DNA

(2012) Swagata Banerjee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Naphthalimide-Tagged Ruthenium–Arene Anticancer Complexes: Combining Coordination with Intercalation

(2012) Kelly J. Kilpin et al.   ORGANOMETALLICS

Synthesis and photophysical evaluations of fluorescent quaternary bipyridyl-1,8-naphthalimide conjugates as nucleic acid targeting agents

(2012) Gary J. Ryan et al.   SUPRAMOLECULAR CHEMISTRY

Development of a fluorogenic sensor for activated Cdc42

(2011) Brenda N. Goguen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel efficient anticancer agents and DNA-intercalators of 1,2,3-triazol-1,8-naphthalimides: design, synthesis, and biological activity

(2011) Xiaolian Li et al.   TETRAHEDRON

B1-induced caspase-independent apoptosis in MCF-7 cells is mediated by down-regulation of Bcl-2 via p53 binding to P2 promoter TATA box

(2011) Xin Liang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effect of the bases flanking an abasic site on the recognition of nucleobase by amiloride

(2010) Arivazhagan Rajendran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior

(2010) Lijuan Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Quaternarized pdppz: synthesis, DNA-binding and biological studies of a novel dppz derivative that causes cellular death upon light irradiation

(2010) Robert B. P. Elmes et al.   CHEMICAL COMMUNICATIONS

Colorimetric and fluorescent anion sensors: an overview of recent developments in the use of 1,8-naphthalimide-based chemosensors

(2010) Rebecca M. Duke et al.   CHEMICAL SOCIETY REVIEWS

Optical, Redox, and DNA-Binding Properties of Phenanthridinium Chromophores: Elucidating the Role of the Phenyl Substituent for Fluorescence Enhancement of Ethidium in the Presence of DNA

(2010) Christa Prunkl et al.   CHEMISTRY-A EUROPEAN JOURNAL

A New Class of Naphthalimide-Based Antitumor Agents That Inhibit Topoisomerase II and Induce Lysosomal Membrane Permeabilization and Apoptosis

(2010) Zhuo Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Photophysical, and DNA Binding Studies of Fluorescent Tröger’s Base Derived 4-Amino-1,8-naphthalimide Supramolecular Clefts

(2010) Emma B. Veale et al.   JOURNAL OF ORGANIC CHEMISTRY

Thiol-Reactive Derivatives of the Solvatochromic 4-N,N-Dimethylamino-1,8-naphthalimide Fluorophore: A Highly Sensitive Toolset for the Detection of Biomolecular Interactions

(2009) Galen Loving et al.   BIOCONJUGATE CHEMISTRY

NBD-Based Green Fluorescent Ligands for Typing of Thymine-Related SNPs by Using an Abasic Site-Containing Probe DNA

(2009) Viruthachalam Thiagarajan et al.   CHEMBIOCHEM

Electronic Properties of 4-Substituted Naphthalimides

(2009) Pavel Kucheryavy et al.   JOURNAL OF PHYSICAL CHEMISTRY A

4-Amino-1,8-naphthalimide-Based Tröger’s Bases As High Affinity DNA Targeting Fluorescent Supramolecular Scaffolds

(2009) Emma B. Veale et al.   ORGANIC LETTERS

Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors

(2009) Raman Parkesh et al.   TETRAHEDRON LETTERS

Simultaneous recognition of nucleobase and sites of DNA damage: Effect of tethered cation on the binding affinity

(2008) Arivazhagan Rajendran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells

(2008) Ingo Ott et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel naphthalimide–amino acid conjugates with flexible leucine moiety as side chain: Design, synthesis and potential antitumor activity

(2008) Aibin Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Naphthalimide intercalators with chiral amino side chains: Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity

(2008) Qing Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents

(2008) Zhi-yong Tian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Versatile Amino Acid Analogue of the Solvatochromic Fluorophore 4-N,N-Dimethylamino-1,8-naphthalimide: A Powerful Tool for the Study of Dynamic Protein Interactions

(2008) Galen Loving et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anion-π interactions

(2007) Brandi L. Schottel et al.   CHEMICAL SOCIETY REVIEWS

Highly Effective DNA Photocleavage by Novel “Rigid” Ru(bpy)3-4-nitro- and -4-amino-1,8-naphthalimide Conjugates

(2007) Gary J. Ryan et al.   INORGANIC CHEMISTRY