Synthesis and structural studies of S-type/N-type-locked/frozen nucleoside analogues and their incorporation in RNA-selective, nuclease resistant 2′–5′ linked oligonucleotides

Single-Stranded siRNAs Activate RNAi in Animals

(2012) Walt F. Lima et al.   CELL

Activated Ribonucleotides Undergo a Sugar Pucker Switch upon Binding to a Single-Stranded RNA Template

(2012) Na Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing the furanose conformation in the 2′–5′strand of isoDNA : RNA duplexes by freezing the nucleoside conformations

(2011) Namrata Erande et al.   CHEMICAL COMMUNICATIONS

Carba-LNA modified siRNAs targeting HIV-1 TAR region downregulate HIV-1 replication successfully with enhanced potency

(2011) Suman Dutta et al.   MedChemComm

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

5′-O-Dephosphorylated 2′,5′-oligoadenylate (2-5A) with 8-methyladenosine at the 2′-terminus activates human RNase L

(2009) Kumi Nagaoka et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent Approaches in the Synthesis of Conformationally Restricted Nucleoside Analogues

(2008) Christophe Mathé et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY