Article
Dentistry, Oral Surgery & Medicine
Blanca Estevez-Arroyo, Ignacio Gomez-Mendo, Martin Romero-Maroto, Enrique Solano-Reina, Alejandro Iglesias-Linares
Summary: Patients with Van der Woude syndrome exhibit specific craniofacial characteristics, including a tendency towards vertical growth pattern, skeletal class II caused by mandibular retrognathism, retruded and retroclined lower incisors, increased interincisal angulation, an open nasolabial angle, and a more protruding lower lip.
Review
Medicine, General & Internal
Anders Edsjo, Louise Holmquist, Birgit Geoerger, Frederique Nowak, Georgy Gomon, Catherine Alix-Panabieres, Carolin Ploeger, Ulrik Lassen, Christophe Le Tourneau, Janne Lehtio, Patrick A. Ott, Andreas von Deimling, Stefan Froehling, Emile Voest, Frederick Klauschen, Rodrigo Dienstmann, Aisha Alshibany, Lillian L. Siu, Albrecht Stenzinger
Summary: Precision cancer medicine requires the involvement and commitment of many stakeholders and can be improved through advancements in molecular diagnostics and clinical trial concepts. Adaptive profiling strategies and early detection approaches are becoming routine in patient management. Collaborative efforts and multicentric networks are crucial in implementing precision oncology in practice.
JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Oncology
Yalan Zhang, Calixto-Hope G. Lucas, Jacob S. Young, Ramin A. Morshed, Lucie McCoy, Nancy Ann Oberheim Bush, Jennie W. Taylor, Mariza Daras, Nicholas A. Butowski, Javier E. Villanueva-Meyer, Soonmee Cha, Margaret Wrensch, John K. Wiencke, Julieann C. Lee, Melike Pekmezci, Joanna J. Phillips, Arie Perry, Andrew W. Bollen, Manish K. Aghi, Philip Theodosopoulos, Edward F. Chang, Shawn L. Hervey-Jumper, Mitchel S. Berger, Jennifer L. Clarke, Susan M. Chang, Annette M. Molinaro, David A. Solomon
Summary: Genomic profiling of diffuse astrocytic gliomas can better predict patient outcomes compared to histomorphology alone. This study found that the integration of genomic profiling with radiologic and histologic features can lead to improved patient management and clinical outcomes for IDH-wildtype glioblastoma. This supports the routine use of genomic profiling in accurately classifying glial neoplasms.
Review
Cell Biology
Elahe Tahmasebi, Mehdi Mohammadi, Mostafa Alam, Kamyar Abbasi, Saeed Gharibian Bajestani, Rojin Khanmohammad, Mohsen Haseli, Mohsen Yazdanian, Peyman Esmaeili Fard Barzegar, Hamid Tebyaniyan
Summary: Craniofacial deformities (CFDs) can occur as a result of oncological resection, trauma, or congenital disorders. Trauma, which varies in rates across countries, is a leading cause of death globally. CFDs lead to non-healing composite tissue wounds as they deteriorate in soft or hard tissues. Gum disease is responsible for approximately one-third of oral diseases. The complex anatomical structures and tissue-specific requirements in the craniofacial region pose numerous challenges for CFD treatments. Various treatment methods, including drugs, regenerative medicine, surgery, and tissue engineering, are available for CFDs.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Medicine, General & Internal
Nicole Culos-Reed, Chad W. Wagoner, Julianna Dreger, Margaret L. McNeely, Melanie Keats, Daniel Santa Mina, Colleen Cuthbert, Lauren C. Capozzi, George J. Francis, Guanmin Chen, Manuel Ester, Emma McLaughlin, Max Eisele, Daniel Sibley, Jodi Langley, Joy Chiekwe, Thomas Christensen
Summary: This article introduces the EXCEL study, which aims to improve accessibility to exercise oncology programs for cancer patients in rural and remote areas. The study uses a hybrid effectiveness-implementation approach, with clinical exercise physiologists providing knowledge support to healthcare professionals and community-based qualified exercise professionals for education, referrals, and programming. The impact of EXCEL is evaluated using the RE-AIM framework at participant and institutional levels, assessing physical activity, functional fitness, and patient-reported outcomes.
Review
Medicine, General & Internal
Hong-Juan Fu, Hao Zhou, Yong Tang, Jie Li, Da Zhang, Song-Yi Ding, Qin-Wan Huang, Chao Wang
Summary: This article discusses the efficacy of Tai Chi and other mind-body interventions in the treatment of cancer-related fatigue, and proposes a systematic review and network meta-analysis to assess their effects.
Article
Medicine, General & Internal
Elena Sultova, C. Benedikt Westphalen, Andreas Jung, Joerg Kumbrink, Thomas Kirchner, Doris Mayr, Martina Rudelius, Steffen Ormanns, Volker Heinemann, Klaus H. Metzeler, Philipp A. Greif, Anna Hester, Sven Mahner, Nadia Harbeck, Rachel Wuerstlein
Summary: The establishment of a Molecular Tumor Board to provide personalized treatment recommendations based on molecular diagnostics has shown to be beneficial for metastatic breast cancer patients, with a high percentage of tumors having actionable genetic alterations and a significant number of patients experiencing clinical benefit from targeted therapies recommended by the board.
Article
Medicine, General & Internal
Mengqi Xiang, Huachuan Zhang, Lingna Kou, Jing Chen, Zhihua Xu, Jintao He
Summary: High levels of complement factor H (CFH) were found to decrease the risk of death in patients with non-small-cell lung cancer (SCLC), while elevated complement C4 levels displayed poor prognosis. A predictive model based on CFH, C3, and C4 levels was constructed, showing good accuracy in assessing patients' prognostic outcomes.
POSTGRADUATE MEDICAL JOURNAL
(2022)
Review
Oncology
Simon Haefliger, Vanghelita Andrei, Daniel Baumhoer
Summary: The craniofacial skeleton is a complex anatomical region containing bone sarcomas that differ from peripheral counterparts. Involvement of a multidisciplinary team is necessary for optimal diagnosis and treatment planning. Advances in molecular characterization have increased diagnostic accuracy and hold promise for identifying therapeutic targets.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Jan Valentini, Daniela Frohlich, Regina Stolz, Cornelia Mahler, Peter Martus, Nadja Klafke, Markus Horneber, Jona Frasch, Klaus Kramer, Hartmut Bertz, Barbara Grun, Katrin Tomaschko-Ubelander, Stefanie Joos, CCC-Integrativ Study Group
Summary: This study aims to develop and evaluate an interprofessional counselling program on complementary and integrative healthcare (CIH) for patients with cancer. The program includes interventions on patient, provider, and system levels, and will be evaluated using a multilayer evaluation design.
Review
Medicine, General & Internal
Jing Xu, Hong Li, Daniel Man-yuen Sze, Vincent Wan Shing Chan, Angela Wei Hong Yang
Summary: This umbrella review aims to analyze and synthesize published systematic reviews and meta-analyses on the effectiveness of Qigong and tai chi in improving the quality of life of patients with cancer.
Review
Oncology
Bonnie E. Gould Rothberg, Tammie E. Quest, Sai-Ching J. Yeung, Lorraine C. Pelosof, David E. Gerber, Justin A. Seltzer, Jason J. Bischof, Charles R. Thomas, Nausheen Akhter, Mira Mamtani, Robin E. Stutman, Christopher W. Baugh, Venkataraman Anantharaman, Nicholas R. Pettit, Adam D. Klotz, Michael A. Gibbs, Demetrios N. Kyriacou
Summary: This article comprehensively reviews oncologic emergencies and urgencies encountered in acute care settings, discussing clinical pathways and patient outcomes. It covers a wide range of topics including complications associated with tumors, targeted therapeutics, and strategies for direct admission to hospice.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Public, Environmental & Occupational Health
Yek-Ching Kong, Merel Kimman, ShriDevi Subramaniam, Cheng-Har Yip, Stephen Jan, Soe Aung, Mai Trong Khoa, Corazon A. Ngelangel, Htun Lwin Nyein, Suleeporn Sangrajrang, Jitraporn Tanabodee, Nirmala Bhoo-Pathy
Summary: This study investigates the patterns of out-of-pocket spending on complementary medicine among cancer patients in middle-income countries in southeast Asia. The findings suggest that expenditures on complementary medicine are associated with adverse financial outcomes.
LANCET GLOBAL HEALTH
(2022)
Article
Medicine, General & Internal
Andreas Palm, J. Theorell-Haglow, Johan Isakson, Mirjam Ljunggren, Josefin Sundh, Magnus Per Ekstrom, Ludger Grote
Summary: This cross-sectional study investigated the association between OSA measures and cancer prevalence in a large patient cohort in Sweden. The results showed that OSA patients with cancer had higher AHI and ODI compared to matched OSA patients without cancer. Subgroup analysis also revealed higher ODI in OSA patients with lung cancer, prostate cancer, and malignant melanoma.
Article
Medicine, General & Internal
Gashaw Yada Hundie, Endalew G. Sendo, Teshome Habte
Summary: This study explores women's sexual experiences and coping strategies for sexual problems after gynaecological treatment. The study reveals four main themes, including treatment side effects, sexual issues following radiation therapy, lack of awareness regarding cancer treatment and sexual dysfunction, and coping strategies for sexual dysfunction following gynaecological cancer treatment. Three sub-themes emerge as coping mechanisms for managing sexual issues and dysfunction among Ethiopian women with gynaecological cancer: avoiding sexual intercourse, praying for healing and seeking professional help.
Review
Oncology
Harry Karna, Jaime Gonzalez, Harveen S. Radia, Parish P. Sedghizadeh, Reyes Enciso
Article
Oncology
Atlas Khan, Qian Liu, Xuelian Chen, Andres Stucky, Parish P. Sedghizadeh, Daniel Adelpour, Xi Zhang, Kai Wang, Jiang F. Zhong
MOLECULAR ONCOLOGY
(2019)
Article
Dentistry, Oral Surgery & Medicine
Jordan Roszhart, Satish S. Kumar, Veerasathpurush Allareddy, Christopher A. Childs, Satheesh Elangovan
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2020)
Letter
Dentistry, Oral Surgery & Medicine
Allan C. Jones, Parish P. Sedghizadeh
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2020)
Review
Dermatology
Joel M. Laudenbach, Satish S. Kumar
DERMATOLOGIC CLINICS
(2020)
Editorial Material
Dentistry, Oral Surgery & Medicine
Satish Kumar, Diane Paz
JOURNAL OF DENTAL EDUCATION
(2021)
Review
Dentistry, Oral Surgery & Medicine
Julie Frantsve-Hawley, Satish S. Kumar, D. Brad Rindal, Robert J. Weyant
PERIODONTOLOGY 2000
(2020)
Article
Dentistry, Oral Surgery & Medicine
Yingci Liu, Nilesh Shah, Kurt Summersgill, Satish Kumar
Summary: The study found that individuals with prior oral dysplasia had significantly higher odds for locoregional recurrence, while OSCC of the tongue and floor of the mouth had lower recurrence odds compared to other sites. Histologic grade, depth of invasion, and elective neck dissection did not seem to influence locoregional recurrence for T1N0 tumors.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2021)
Editorial Material
Dentistry, Oral Surgery & Medicine
Elliot Abt, Satish Kumar, Robert J. Weyant
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2022)
Article
Biochemistry & Molecular Biology
Parish P. P. Sedghizadeh, Philip Cherian, Sahar Roshandel, Natalia Tjokro, Casey Chen, Adam E. F. Junka, Eric Hu, Jeffrey Neighbors, Jacek Pawlak, R. Graham G. Russell, Charles E. E. McKenna, Frank H. H. Ebetino, Shuting Sun, Esmat Sodagar
Summary: Osteomyelitis is a severe orthopedic infection caused by Staphylococcus aureus biofilms. Novel antibiotic conjugates comprising bone-binding bisphosphonates were designed and tested for their effectiveness against biofilm growth in this study. The conjugates demonstrated dose-dependent antimicrobial activity and retained bone-binding properties as well as the antimicrobial activity of the parent antibiotic, although at lower levels due to chemical modification. These findings are important for the development of new drugs for osteomyelitis treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Satish S. Kumar, Husain Mohammad, Kian Kar
CLINICAL ADVANCES IN PERIODONTICS
(2020)
Meeting Abstract
Endocrinology & Metabolism
Parish Sedghizadeh, Esmat Sodagar, Raffle Garabedian, Jasveen Wadia, Frank Ebetino, Philip Cherian, Shuting Sun, Neema Bakhshalian, Jeffrey Neighbors, R. Graham Russell, Charles McKenna
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Article
Acoustics
Colman Moore, Yuting Bai, Ali Hariri, Joan B. Sanchez, Ching-Yu Lin, Sreenivas Koka, Parish Sedghizadeh, Casey Chen, Jesse Jokerst
Meeting Abstract
Endocrinology & Metabolism
Jayesh Shah, Frank H. Ebetino, Lianping Xing, Robert Boeckman, Shuting Sun, Parish Sedghizadeh, Michael T. Yin, Suzanne Lentzsch, Graham Russell, Serge Cremers
JOURNAL OF BONE AND MINERAL RESEARCH
(2018)
Article
Dentistry, Oral Surgery & Medicine
Erin N. Schwoegl, Mackenzie E. Rodgers, Satish S. Kumar
JOURNAL OF DENTAL EDUCATION
(2020)
