BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

(2018) Chaoyang Sun et al.   CANCER CELL

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

(2017) Takao Fujisawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer

(2017) Sergey Karakashev et al.   Cell Reports

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

(2016) Alejandra Bruna et al.   CELL

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

(2016) Shaokun Shu et al.   NATURE

Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis

(2015) Blake R Wilde et al.   BRITISH JOURNAL OF CANCER

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP

(2015) Liangliang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer

(2014) Jennifer A Morrison et al.   Molecular Cancer

Prevalence of BRCA Mutations Among Women with Triple-Negative Breast Cancer (TNBC) in a Genetic Counseling Cohort

(2013) Rachel Greenup et al.   ANNALS OF SURGICAL ONCOLOGY

Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma

(2013) Z. Cheng et al.   CLINICAL CANCER RESEARCH

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

(2013) Chiara Gorrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thioredoxin interacting protein and its association with clinical outcome in gastro-oesophageal adenocarcinoma

(2013) Caroline M. Woolston et al.   Redox Biology

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

(2012) Wanjuan Yang et al.   NUCLEIC ACIDS RESEARCH

Thioredoxin-interacting protein suppresses bladder carcinogenesis

(2011) Koji Nishizawa et al.   CARCINOGENESIS

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Importance of mitochondrial dysfunction in oxidative stress response: A comparative study of gene expression profiles

(2011) Motoko Shibanuma et al.   FREE RADICAL RESEARCH

ROS Quenching Potential of the Epidermal Cornified Cell Envelope

(2011) Wilbert P. Vermeij et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Cornified Envelope: A First Line of Defense against Reactive Oxygen Species

(2011) Matthias Schäfer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TXNIP potentiates Redd1-induced mTOR suppression through stabilization of Redd1

(2011) H-O Jin et al.   ONCOGENE

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

(2008) Gary LeRoy et al.   MOLECULAR CELL

Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy

(2008) Kathryn F. Tonissen et al.   MOLECULAR NUTRITION & FOOD RESEARCH