Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer

Role of TRPM2 in cell proliferation and susceptibility to oxidative stress

(2013) Shu-jen Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A 36-gene Signature Predicts Clinical Progression in a Subgroup of ERG-positive Prostate Cancers

(2013) Delila Gasi Tandefelt et al.   EUROPEAN UROLOGY

Effects of Screening on Radical Prostatectomy Efficacy: The Prostate Cancer Intervention Versus Observation Trial

(2013) Jing Xia et al.   JNCI-Journal of the National Cancer Institute

A Molecular Signature Predictive of Indolent Prostate Cancer

(2013) S. Irshad et al.   Science Translational Medicine

A 12-Gene Expression Signature Is Associated with Aggressive Histological in Prostate Cancer

(2012) Laia Agell et al.   AMERICAN JOURNAL OF PATHOLOGY

Control of somatic tissue differentiation by the long non-coding RNA TINCR

(2012) Markus Kretz et al.   NATURE

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death

(2012) S. Verma et al.   NEUROSCIENCE LETTERS

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

(2012) K Kim et al.   ONCOGENE

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling

(2011) Jan C Brase et al.   BMC CANCER

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

mRNA Expression Signature of Gleason Grade Predicts Lethal Prostate Cancer

(2011) Kathryn L. Penney et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study

(2011) Jack Cuzick et al.   LANCET ONCOLOGY

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

lincRNAs act in the circuitry controlling pluripotency and differentiation

(2011) Mitchell Guttman et al.   NATURE

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

(2011) Anke Di et al.   NATURE IMMUNOLOGY

Current prospects for RNA interference-based therapies

(2011) Beverly L. Davidson et al.   NATURE REVIEWS GENETICS

Cysteine-Rich Secretory Protein-3 (CRISP3) Is Strongly Up-Regulated in Prostate Carcinomas with the TMPRSS2-ERG Fusion Gene

(2011) Franclim R. Ribeiro et al.   PLoS One

Molecular classification of prostate cancer using curated expression signatures

(2011) E. K. Markert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture

(2010) Ji-Zhong Bai et al.   NEUROTOXICOLOGY

Outcomes of Localized Prostate Cancer Following Conservative Management

(2009) Grace L. Lu-Yao   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Use of Archived Specimens in Evaluation of Prognostic and Predictive Biomarkers

(2009) R. M. Simon et al.   JNCI-Journal of the National Cancer Institute

The use of PCA3 in the diagnosis of prostate cancer

(2009) Daphne Hessels et al.   Nature Reviews Urology

Novel role for the transient receptor potential channel TRPM2 in prostate cancer cell proliferation

(2009) X Zeng et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Identification of novel sense and antisense transcription at the TRPM2 locus in cancer

(2008) Ugo Orfanelli et al.   CELL RESEARCH

Gene Panel Model Predictive of Outcome in Men at High-Risk of Systemic Progression and Death From Prostate Cancer After Radical Retropubic Prostatectomy

(2008) John C. Cheville et al.   JOURNAL OF CLINICAL ONCOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

(2008) Shinichiro Yamamoto et al.   NATURE MEDICINE

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA