Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells

(2013) Carolyn A. Goard et al.   BREAST CANCER RESEARCH AND TREATMENT

Efficient Use of Exogenous Isoprenols for Protein Isoprenylation by MDA-MB-231 Cells Is Regulated Independently of the Mevalonate Pathway

(2013) Fredrick Onono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efectos de las estatinas en cáncer: ¿potencial rol en terapéutica y prevención?

(2013) Mauricio Cuello F et al.   REVISTA MEDICA DE CHILE

Regulation of the Hippo pathway and implications for anticancer drug development

(2013) Hyun Woo Park et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cellular Heterogeneity and Molecular Evolution in Cancer

(2012) Vanessa Almendro et al.   Annual Review of Pathology-Mechanisms of Disease

Lysophospholipid receptor activation of RhoA and lipid signaling pathways

(2012) Sunny Yang Xiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

(2012) B. Zhao et al.   GENES & DEVELOPMENT

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

(2012) J. M. Lamar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of YAP protein domains reveal promising targets for development of new cancer drugs

(2012) Marius Sudol et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

(2011) Wenyi Mi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Frequent epigenetic inactivation ofKIBRA,an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia

(2011) Victoria K. Hill et al.   Epigenetics

A Critical Role of Gβγ in Tumorigenesis and Metastasis of Breast Cancer

(2011) Xiaoyun Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene

(2011) X Zhang et al.   ONCOGENE

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

(2010) S. Benhamouche et al.   GENES & DEVELOPMENT

G Protein βγ Subunits Regulate Cell Adhesion through Rap1a and Its Effector Radil

(2010) Syed M. Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G   Signaling Promotes Breast Cancer Cell Migration and Invasion

(2010) J. K. Kirui et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer

(2009) Elisabeth R. Garwood et al.   BREAST CANCER RESEARCH AND TREATMENT

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen Receptor-Negative Breast Cancer Is Less Likely to Arise among Lipophilic Statin Users

(2008) A. S. Kumar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

(2008) V. Serra et al.   CANCER RESEARCH

A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells

(2008) S. W. Chan et al.   CANCER RESEARCH

G protein βγ subunits: Central mediators of G protein-coupled receptor signaling

(2008) A. V. Smrcka   CELLULAR AND MOLECULAR LIFE SCIENCES

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Expression of Yes-associated protein in common solid tumors

(2008) Angela A. Steinhardt et al.   HUMAN PATHOLOGY

Mst2 and Lats Kinases Regulate Apoptotic Function of Yes Kinase-associated Protein (YAP)

(2008) Tsutomu Oka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY