Mitochondrial retrograde signaling induces epithelial–mesenchymal transition and generates breast cancer stem cells

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Silencing of I k Bβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo

(2012) Weigang Tang et al.   CARCINOGENESIS

mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination

(2012) W. Fan et al.   GENES & DEVELOPMENT

Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APCMin/+ Mice

(2011) Dong Kyun Woo et al.   AMERICAN JOURNAL OF PATHOLOGY

Frequent Truncating Mutation of TFAM Induces Mitochondrial DNA Depletion and Apoptotic Resistance in Microsatellite-Unstable Colorectal Cancer

(2011) J. Guo et al.   CANCER RESEARCH

Mitochondrial DNA and disease

(2011) Laura C Greaves et al.   JOURNAL OF PATHOLOGY

Mitochondrial DNA Mutations Regulate Metastasis of Human Breast Cancer Cells

(2011) Hirotake Imanishi et al.   PLoS One

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets

(2010) Manti Guha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion

(2010) Mariola Kulawiec et al.   CANCER BIOLOGY & THERAPY

An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition

(2010) Claude C Warzecha et al.   EMBO JOURNAL

Modeling metastasis biology and therapy in real time in the mouse lung

(2010) Arnulfo Mendoza et al.   JOURNAL OF CLINICAL INVESTIGATION

Breast Cancer Among the Oldest Old: Tumor Characteristics, Treatment Choices, and Survival

(2010) Mara A. Schonberg et al.   JOURNAL OF CLINICAL ONCOLOGY

Mitochondrial DNA depletion and its correlation with TFAM, TFB1M, TFB2M and POLG in human diffusely infiltrating astrocytomas

(2010) R.L. Correia et al.   MITOCHONDRION

Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

(2010) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events

(2010) Claude C. Warzecha et al.   RNA Biology

Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

(2009) Peng Xia et al.   BMC CANCER

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells

(2009) Man Yu et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Heterogeneous Nuclear Ribonucleoprotein A2 Is a Common Transcriptional Coactivator in the Nuclear Transcription Response to Mitochondrial Respiratory Stress

(2009) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

(2009) Claude C. Warzecha et al.   MOLECULAR CELL

mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

(2008) Darren Magda et al.   BMC GENOMICS

Progressive tumor features accompany epithelial-mesenchymal transition induced in mitochondrial DNA-depleted cells

(2008) Akihiro Naito et al.   CANCER SCIENCE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2

(2008) L Moro et al.   CELL DEATH AND DIFFERENTIATION

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE

ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

(2008) K. Ishikawa et al.   SCIENCE