Silencing of I k Bβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo

Nuclear Factor-κB (NF-κB) Inhibitory Protein IκBβ Determines Apoptotic Cell Death following Exposure to Oxidative Stress

(2012) Clyde J. Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Frequent Truncating Mutation of TFAM Induces Mitochondrial DNA Depletion and Apoptotic Resistance in Microsatellite-Unstable Colorectal Cancer

(2011) J. Guo et al.   CANCER RESEARCH

Somatic mutations of mitochondrial DNA in aging and cancer progression

(2010) Hsin-Chen Lee et al.   AGEING RESEARCH REVIEWS

Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets

(2010) Manti Guha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

(2010) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

IκBβ acts to inhibit and activate gene expression during the inflammatory response

(2010) Ping Rao et al.   NATURE

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

(2009) Claudia Scholl et al.   CELL

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

(2009) Ji Luo et al.   CELL

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis

(2009) J. S. Park et al.   HUMAN MOLECULAR GENETICS

Mutations in mitochondrial DNA polymerase-γ promote breast tumorigenesis

(2009) Keshav K Singh et al.   JOURNAL OF HUMAN GENETICS

Heterogeneous Nuclear Ribonucleoprotein A2 Is a Common Transcriptional Coactivator in the Nuclear Transcription Response to Mitochondrial Respiratory Stress

(2009) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

Progressive tumor features accompany epithelial-mesenchymal transition induced in mitochondrial DNA-depleted cells

(2008) Akihiro Naito et al.   CANCER SCIENCE

Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2

(2008) L Moro et al.   CELL DEATH AND DIFFERENTIATION

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling

(2008) Gopa Biswas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA Content: Its Genetic Heritability and Association With Renal Cell Carcinoma

(2008) J. Xing et al.   JNCI-Journal of the National Cancer Institute