cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Cdc42 and the Guanine Nucleotide Exchange Factors Ect2 and Trio Mediate Fn14-Induced Migration and Invasion of Glioblastoma Cells

(2012) S. P. Fortin et al.   MOLECULAR CANCER RESEARCH

Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator

(2012) Min Zhuang et al.   MOLECULAR CELL

Essential Role of Cdc42 in Ras-Induced Transformation Revealed by Gene Targeting

(2012) Kristy R. Stengel et al.   PLoS One

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

(2011) Kristy Stengel et al.   CELLULAR SIGNALLING

The regulation of TNF signalling: what a tangled web we weave

(2011) John Silke   CURRENT OPINION IN IMMUNOLOGY

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

(2011) Tripat Kaur Oberoi et al.   EMBO JOURNAL

Off the beaten paths: alternative and crosstalk regulation of Rho GTPases

(2011) Etienne Boulter et al.   FASEB JOURNAL

TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway

(2011) S. Kant et al.   GENES & DEVELOPMENT

X-linked Inhibitor of Apoptosis Protein (XIAP) Mediates Cancer Cell Motility via Rho GDP Dissociation Inhibitor (RhoGDI)-dependent Regulation of the Cytoskeleton

(2011) Jinyi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription

(2011) Jessy Cartier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

(2011) Eleni Makrodouli et al.   Molecular Cancer

CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration

(2011) Juanita Lopez et al.   MOLECULAR CELL

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuropilin-2 Expression Promotes TGF-β1-Mediated Epithelial to Mesenchymal Transition in Colorectal Cancer Cells

(2011) Camille Grandclement et al.   PLoS One

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

(2010) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

(2010) Jasmin N Dynek et al.   EMBO JOURNAL

Asymmetric Recruitment of cIAPs by TRAF2

(2010) Peter D. Mace et al.   JOURNAL OF MOLECULAR BIOLOGY

Compartmentalized Ras Proteins Transform NIH 3T3 Cells with Different Efficiencies

(2010) C.-M. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

(2010) Etienne Boulter et al.   NATURE CELL BIOLOGY

Cdc42 Regulates Microtubule-Dependent Golgi Positioning

(2010) Heidi Hehnly et al.   TRAFFIC

Looking beyond death: a morphogenetic role for the TNF signalling pathway

(2009) S. J. Mathew et al.   JOURNAL OF CELL SCIENCE

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

(2009) Tobias L. Haas et al.   MOLECULAR CELL

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Ins and outs of ADF/cofilin activity and regulation

(2008) M VANTROYS et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

(2008) Eugene Varfolomeev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

(2008) Taner Dogan et al.   NATURE CELL BIOLOGY

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis

(2008) Mads Gyrd-Hansen et al.   NATURE CELL BIOLOGY

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY