Essential Role of Cdc42 in Ras-Induced Transformation Revealed by Gene Targeting

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

(2011) Kristy Stengel et al.   CELLULAR SIGNALLING

Cancer therapy based on oncogene addiction

(2011) Frank McCormick   JOURNAL OF SURGICAL ONCOLOGY

Rac1 targeting suppresses p53 deficiency-mediated lymphomagenesis

(2010) E. E. Bosco et al.   BLOOD

Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts

(2010) Daniel M Appledorn et al.   BMC CANCER

Signaling Role of Cdc42 in Regulating Mammalian Physiology

(2010) Jaime Melendez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compartmentalized Ras Proteins Transform NIH 3T3 Cells with Different Efficiencies

(2010) C.-M. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

(2009) Claudia Scholl et al.   CELL

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

(2009) Ji Luo et al.   CELL

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

FAK Phosphorylation by ERK Primes Ras-Induced Tyrosine Dephosphorylation of FAK Mediated by PIN1 and PTP-PEST

(2009) Yanhua Zheng et al.   MOLECULAR CELL

Ras/MAPK signaling from endomembranes

(2009) Nicole Fehrenbacher et al.   Molecular Oncology

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

RAS: Target for Cancer Therapy

(2008) Nandita Saxena et al.   CANCER INVESTIGATION