Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

EGFR mediates LPA-induced proteolytic enzyme expression and ovarian cancer invasion: Inhibition by resveratrol

(2012) Kang Jin Jeong et al.   Molecular Oncology

Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers

(2012) Anna L. Stratford et al.   STEM CELLS

Low-grade serous carcinomas of the ovary contain very few point mutations

(2011) Siân Jones et al.   JOURNAL OF PATHOLOGY

YB-1, the E2F Pathway, and Regulation of Tumor Cell Growth

(2011) Annette Lasham et al.   JNCI-Journal of the National Cancer Institute

Comprehensive Predictive Biomarker Analysis for MEK Inhibitor GSK1120212

(2011) J. Jing et al.   MOLECULAR CANCER THERAPEUTICS

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Location, location, location: a crystal-clear view of autotaxin saturating LPA receptors

(2011) Adel Tabchy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

(2011) Y Lu et al.   ONCOGENE

Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression

(2010) N Panupinthu et al.   BRITISH JOURNAL OF CANCER

An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo

(2010) Craig Cherrin et al.   CANCER BIOLOGY & THERAPY

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Molecular Decoy to the Y-Box Binding Protein-1 Suppresses the Growth of Breast and Prostate Cancer Cells whilst Sparing Normal Cell Viability

(2010) Jennifer H. Law et al.   PLoS One

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

(2010) K. Ericson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells

(2010) Karsten Jürchott et al.   PLoS Genetics

Epidermal growth factor increases lysophosphatidic acid production in human ovarian cancer cells: roles for phospholipase D2 and receptor transactivation

(2009) Ashley J. Snider et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Serial dilution curve: a new method for analysis of reverse phase protein array data

(2009) L. Zhang et al.   BIOINFORMATICS

Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition

(2009) Valentina Evdokimova et al.   CANCER CELL

Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation

(2009) A. Talavera et al.   CANCER RESEARCH

Amphiregulin Promotes BAX Inhibition and Resistance to Gefitinib in Non-small-cell Lung Cancers

(2009) Benoît Busser et al.   MOLECULAR THERAPY

Screening for Ovarian Cancer

(2009) Daniel L. Clarke-Pearson   NEW ENGLAND JOURNAL OF MEDICINE

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

(2009) Doris R. Siwak et al.   Journal of Oncology

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

(2008) N. Rhodes et al.   CANCER RESEARCH

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

(2008) R. W. Tothill et al.   CLINICAL CANCER RESEARCH

Multiple Mechanisms Are Responsible for Transactivation of the Epidermal Growth Factor Receptor in Mammary Epithelial Cells

(2008) Karin D. Rodland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysophosphatidic Acid Receptors Determine Tumorigenicity and Aggressiveness of Ovarian Cancer Cells

(2008) Shuangxing Yu et al.   JNCI-Journal of the National Cancer Institute

Effect ofBRCA1/2Mutations on Long-Term Survival of Patients With Invasive Ovarian Cancer: The National Israeli Study of Ovarian Cancer

(2007) Angela Chetrit et al.   JOURNAL OF CLINICAL ONCOLOGY